Shanghai Escugen and SunRock Biopharma Collaborate on First-in-Class CCR9-Targeted ADC

Shanghai Escugen and SunRock Biopharma Collaborate on First-in-Class CCR9-Targeted ADC

China-based Shanghai Escugen has partnered with Spain-headquartered SunRock Biopharma, S.L. to co – develop SRB123, a first – in – class antibody – drug conjugate (ADC) targeting C – C motif chemokine receptor 9 (CCR9). This receptor is overexpressed in multiple solid tumors, including pancreatic, ovarian, and lung cancers.

Partnership and Technology Integration

The collaboration combines SunRock’s proprietary SRB1 antibody with Escugen’s EZWi – Fit linker – payload platform. The goal is to develop a highly differentiated candidate tailored for CCR9 – high, high – internalization solid tumors.

Cooperation Framework

Under the agreement, the two companies filed a joint patent application last year and secured mutual licensing options. The primary objective of the collaboration is to generate robust preclinical proof – of – concept data to support the early clinical development of SRB123.-Fineline Info & Tech