Alphamab and 3D Medicines License Envafolimab Rights to Glenmark for Multiple Regions

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Alphamab Oncology (HKG: 9966) and 3D Medicines (HKG: 1244), two Chinese pharmaceutical companies, have announced a licensing agreement with Glenmark Pharmaceuticals Ltd (NSE: GLENMARK). The agreement grants the Indian company exclusive development and commercialization rights to the co-developed drug envafolimab (KN035) in India, Asia Pacific (excluding Singapore, Thailand, Malaysia), Middle East and Africa, Russia, CIS, and Latin America for oncology indications.

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According to the terms of the deal, Glenmark will pay a total of USD 700.8 million, which includes an upfront payment and development, regulatory, and commercialization milestone payments. Additionally, Glenmark will pay single-to-double digit royalties based on net sales.

Envafolimab, the world’s first PD-L1 single-domain antibody and human IgG1 Fc fusion protein capable of subcutaneous injection, was originated by Alphamab Oncology, with 3D Medicines as a co-development partner under a deal signed in January 2019. Simcere Pharmaceutical Group (HKG: 2096) joined the alliance in March 2020, taking on the exclusive responsibility for the commercial promotion of the drug in mainland China.- Flcube.com

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