{"id":11003,"date":"2023-12-01T01:42:00","date_gmt":"2023-11-30T17:42:00","guid":{"rendered":"https:\/\/flcube.com\/?p=11003"},"modified":"2024-11-03T01:44:03","modified_gmt":"2024-11-02T17:44:03","slug":"tg-immunopharma-secures-u-s-fda-ind-approval-for-promising-mab-tgi-5-targeting-multiple-cancers","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=11003","title":{"rendered":"TG ImmunoPharma Secures U.S. FDA IND Approval for Promising mAb TGI-5 Targeting Multiple Cancers"},"content":{"rendered":"\n<p>TG ImmunoPharma Co., Ltd, based in China, has announced that it has received Investigational New Drug (IND) approval from the U.S. FDA for its proprietary monoclonal antibody (mAb), TGI-5. While the specific target of this molecule remains undisclosed, the company claims it could be a potential global first-in-class treatment.<\/p>\n\n\n\n<p>TGI-5 is characterized as an innovative immune checkpoint antibody, demonstrating high anti-tumor activity and favorable medicinal properties. The drug is being developed for indications including liver cancer, colorectal cancer, and lung cancer, among others. Upon binding to its target, TGI-5 is designed to restore the anti-cancer immune functions of natural killer (NK) cells and T cells.<\/p>\n\n\n\n<p>Preclinical studies have indicated that TGI-5 exhibits robust anti-tumor efficacy in animal models, outperforming PD-1 antibodies in conditions such as liver cancer, colorectal cancer, and melanoma. Additionally, TGI-5 has shown synergistic anti-cancer effects when combined with PD-1 therapy. The IND filing was supported by partners Caidya (formerly dMed-Clinipace) and GenScript ProBio, who provided pre-clinical CMC services.- <a href=\"https:\/\/flcube.com\">Flcube.com<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>TG ImmunoPharma Co., Ltd, based in China, has announced that it has received Investigational New&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[16,62,1866],"class_list":["post-11003","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-cancer","tag-clinical-trial-approval-initiation","tag-tg-immunopharma"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>TG ImmunoPharma Secures U.S. FDA IND Approval for Promising mAb TGI-5 Targeting Multiple Cancers - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"TG ImmunoPharma Co., Ltd, based in China, has announced that it has received Investigational New Drug (IND) approval from the U.S. FDA for its proprietary monoclonal antibody (mAb), TGI-5. 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