{"id":1138,"date":"2024-08-02T14:22:25","date_gmt":"2024-08-02T06:22:25","guid":{"rendered":"https:\/\/flcube.com\/?p=1138"},"modified":"2024-10-14T11:18:41","modified_gmt":"2024-10-14T03:18:41","slug":"otsuka-pharmaceutical-to-acquire-us-biotech-jnana-therapeutics-in-1-1-billion-deal","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=1138","title":{"rendered":"Otsuka Pharmaceutical to Acquire US Biotech Jnana Therapeutics in $1.1 Billion Deal"},"content":{"rendered":"\n<p>Otsuka Pharmaceutical Co., Ltd, a leading Japanese pharmaceutical company, has announced the signing of a definitive merger agreement to acquire US-based biotechnology firm Jnana Therapeutics Inc. Upon completion of the deal, Jnana will become a wholly owned subsidiary of Otsuka, with the transaction valued at $800 million in upfront payment to Jnana shareholders. Additionally, Otsuka has committed to potential milestone payments of up to $325 million tied to development and regulatory achievements, with an expected closing in the third quarter of Otsuka&#8217;s fiscal year 2024.<\/p>\n\n\n\n<p>The acquisition is driven by Otsuka&#8217;s interest in Jnana&#8217;s cutting-edge drug discovery platform, RAPID, a next-generation chemoproteomics platform that specializes in identifying medicines for targets that are well-validated but have been difficult to drug. This technology is capable of advancing drug development for a spectrum of challenging targets, including solute carriers (SLCs), transcription factors, and signaling scaffold proteins.<\/p>\n\n\n\n<p>The strategic fit between Jnana&#8217;s innovative approach and Otsuka&#8217;s existing drug discovery methods, particularly those employed by its UK subsidiary Astex Pharmaceuticals, is expected to yield significant synergies. Furthermore, the deal will grant Otsuka control over Jnana&#8217;s pipeline, headlined by JNT-517, a first-in-class allosteric small molecule inhibitor of SLC6A19, which has completed a Phase Ib\/II study for the treatment of phenylketonuria (PKU), a rare genetic disorder.- <a href=\"https:\/\/flcube.com\">Flcube.com<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Otsuka Pharmaceutical Co., Ltd, a leading Japanese pharmaceutical company, has announced the signing of a&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,10],"tags":[30,439,25],"class_list":["post-1138","post","type-post","status-publish","format-standard","hentry","category-company","category-deals","tag-biotech","tag-otsuka-pharmaceutical","tag-potential-first-in-class"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Otsuka Pharmaceutical to Acquire US Biotech Jnana Therapeutics in $1.1 Billion Deal - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Otsuka Pharmaceutical Co., Ltd, a leading Japanese pharmaceutical company, has announced the signing of a definitive merger agreement to acquire US-based biotechnology firm Jnana Therapeutics Inc. 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