{"id":13177,"date":"2023-10-09T18:50:00","date_gmt":"2023-10-09T10:50:00","guid":{"rendered":"https:\/\/flcube.com\/?p=13177"},"modified":"2024-11-17T18:51:51","modified_gmt":"2024-11-17T10:51:51","slug":"eli-lilly-launches-three-new-oncology-programs-targeting-kras-and-nectin-4","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=13177","title":{"rendered":"Eli Lilly Launches Three New Oncology Programs Targeting KRAS and Nectin-4"},"content":{"rendered":"\n

Eli Lilly (NYSE: LLY<\/a>) has announced the initiation of three innovative oncology programs focusing on KRAS and Nectin-4, all of which are currently in the pre-clinical stage. This strategic move highlights Lilly’s commitment to advancing cancer therapies that target specific oncogenic pathways.<\/p>\n\n\n\n

Details of the New Oncology Programs<\/strong><\/p>\n\n\n\n

The new programs include a KRAS G12D inhibitor designed to selectively target this mutation without affecting wild-type KRAS. Additionally, Lilly is developing an isoform-selective molecule that inhibits multiple oncogenic KRAS mutations while sparing wild-type HRAS and NRAS. Furthermore, the company is working on an antibody-drug conjugate (ADC) that features a topoisomerase I (TOPO 1) inhibitor linked to a Nectin-4-targeting antibody, enhancing the potential for targeted cancer treatment.<\/p>\n\n\n\n

Upcoming Data Release and Clinical Plans<\/strong><\/p>\n\n\n\n

Eli Lilly is set to release pre-clinical data on these promising candidates this week. The company aims to advance these programs into clinical trials next year, positioning itself at the forefront of cutting-edge oncology research.-Fineline Info & Tech<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Eli Lilly (NYSE: LLY) has announced the initiation of three innovative oncology programs focusing on…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[35,16,199],"class_list":["post-13177","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-adc-xdc","tag-cancer","tag-eli-lilly"],"yoast_head":"\nEli Lilly Launches Three New Oncology Programs Targeting KRAS and Nectin-4 - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Eli Lilly (NYSE: LLY) has announced the initiation of three innovative oncology programs focusing on KRAS and Nectin-4, all of which are currently in the pre-clinical stage. 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