{"id":14105,"date":"2023-09-08T12:18:00","date_gmt":"2023-09-08T04:18:00","guid":{"rendered":"https:\/\/flcube.com\/?p=14105"},"modified":"2024-11-22T12:32:03","modified_gmt":"2024-11-22T04:32:03","slug":"pfizer-and-valnevas-lyme-disease-vaccine-vla15-shows-promise-as-booster-in-pediatric-trials","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=14105","title":{"rendered":"Pfizer and Valneva’s Lyme Disease Vaccine VLA15 Shows Promise as Booster in Pediatric Trials"},"content":{"rendered":"\n

Partners Pfizer (NYSE: PFE<\/a>) and Valneva SE (NASDAQ: VALN<\/a>) have revealed that their Lyme disease vaccine candidate, VLA15, has demonstrated immunogenicity and safety as a booster shot in individuals aged between 5 and 17 years. The primary scheme resulted in seroconversion rates of 94.6% to 95.3% for all serotypes of Borrelia burgdorferi, with antibody titers increasing 2.0- to 2.7-fold after the booster dose administered at month 18, according to the press release.<\/p>\n\n\n\n

Phase III Development and Regulatory Filing Plans<\/strong>
The Phase III development of the vaccine commenced last year and is still ongoing, positioning VLA15 as the most advanced candidate among its competitors in the race for a Lyme disease vaccine. Pfizer and Valneva are planning regulatory filings for 2026, which would mark a significant step towards bringing this vaccine to market.<\/p>\n\n\n\n

Implications for Lyme Disease Prevention<\/strong>
The positive results from the trials highlight the potential of VLA15 in providing protection against Lyme disease, a condition that poses significant health challenges, particularly in regions where the disease is endemic. The vaccine’s ability to induce a strong immune response and its safety profile in the pediatric age group are crucial factors in the ongoing development and potential approval of VLA15.-Fineline Info & Tech<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Partners Pfizer (NYSE: PFE) and Valneva SE (NASDAQ: VALN) have revealed that their Lyme disease…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[2255,863,68,309,12,2256],"class_list":["post-14105","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-nasdaq-valn","tag-nyse-pfe","tag-pediatric-drugs","tag-pfizer","tag-vaccine","tag-valneva"],"yoast_head":"\nPfizer and Valneva's Lyme Disease Vaccine VLA15 Shows Promise as Booster in Pediatric Trials - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Partners Pfizer (NYSE: PFE) and Valneva SE (NASDAQ: VALN) have revealed that their Lyme disease vaccine candidate, VLA15, has demonstrated immunogenicity and safety as a booster shot in individuals aged between 5 and 17 years. 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