{"id":15118,"date":"2023-08-16T00:21:00","date_gmt":"2023-08-15T16:21:00","guid":{"rendered":"https:\/\/flcube.com\/?p=15118"},"modified":"2024-11-27T00:25:06","modified_gmt":"2024-11-26T16:25:06","slug":"amoy-diagnostics-and-astrazeneca-expand-collaboration-on-companion-diagnostic-development","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=15118","title":{"rendered":"Amoy Diagnostics and AstraZeneca Expand Collaboration on Companion Diagnostic Development"},"content":{"rendered":"\n

China-based Amoy Diagnostics Co., Ltd (AmoyDx, SHE: 300685<\/a>) has announced a new cooperation agreement with UK pharmaceutical major AstraZeneca (AZ, NASDAQ: AZN<\/a>), focusing on the development of a companion diagnostic (CDx). This collaboration builds upon a global strategic master collaboration agreement that was first signed at the end of 2021.<\/p>\n\n\n\n

Development of Human 10 Gene Mutation Joint Detection Kit as a CDx for Enhertu<\/strong>
According to the latest agreement, AmoyDx will develop its human 10 gene mutation joint detection kit, which utilizes reversible end termination sequencing, as a CDx for AstraZeneca’s Enhertu (trastuzumab deruxtecan). Enhertu is a HER2-targeted antibody-drug conjugate (ADC) that was co-developed by AstraZeneca and Daiichi Sankyo. The CDx will be used to screen non-small cell lung cancer (NSCLC) patients for HER2 (ERBB2) mutations, providing a targeted approach to treatment.<\/p>\n\n\n\n

Enhertu’s Approvals and Availability in Oncology Treatments<\/strong>
Enhertu has received approval to treat breast cancer in China and is available for the treatment of gastric cancer and NSCLC in other countries. The development of a companion diagnostic to identify patients who may benefit from Enhertu’s targeted therapy is a significant step forward in personalized medicine and oncology treatment.-Fineline Info & Tech<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

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