{"id":16938,"date":"2024-12-05T22:33:27","date_gmt":"2024-12-05T14:33:27","guid":{"rendered":"https:\/\/flcube.com\/?p=16938"},"modified":"2024-12-05T22:33:30","modified_gmt":"2024-12-05T14:33:30","slug":"eli-lillys-zepbound-outperforms-wegovy-in-surmount-5-weight-loss-study","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=16938","title":{"rendered":"Eli Lilly’s Zepbound Outperforms Wegovy in SURMOUNT-5 Weight Loss Study"},"content":{"rendered":"\n

US pharmaceutical major Eli Lilly & Co., (NYSE: LLY) has revealed a positive readout from the open-label, randomized Phase III SURMOUNT-5 study. The study assessed the weight loss effects of Zepbound (tirzepatide) compared to Wegovy (semaglutide) in adult patients with obesity or overweight, who have at least one weight-related medical problem but do not have diabetes.<\/p>\n\n\n\n

Zepbound Demonstrates Superior Weight Loss Compared to Wegovy<\/strong>
The study results indicated that Zepbound achieved a 47% greater relative weight loss compared to Wegovy, with an average weight loss of 20.2% for Zepbound versus 13.7% for Wegovy. At 72 weeks, Zepbound outperformed Wegovy on both the primary endpoint and all five key secondary endpoints, marking a significant advancement in the treatment of obesity.<\/p>\n\n\n\n

Safety Profiles of Zepbound and Wegovy<\/strong>
In addition to the efficacy results, the safety of both drugs was found to be consistent with previous findings, providing reassurance on their use in long-term weight management.<\/p>\n\n\n\n

Background on Tirzepatide and Semaglutide<\/strong>
Tirzepatide, the active ingredient in Zepbound, is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. It has been approved in multiple countries, including China and the US, for the treatment of type 2 diabetes under the trade name Mounjaro, and for long-term weight management as Zepbound. Semaglutide, a GLP-1 agonist, is approved to treat type 2 diabetes and reduce weight under the trade names Ozempic and Wegovy, respectively.-Fineline Info & Tech<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

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