{"id":17703,"date":"2024-12-12T16:40:40","date_gmt":"2024-12-12T08:40:40","guid":{"rendered":"https:\/\/flcube.com\/?p=17703"},"modified":"2024-12-12T16:40:43","modified_gmt":"2024-12-12T08:40:43","slug":"grand-pharmaceutical-group-secures-licensing-agreement-for-corxels-nasal-sprays-in-greater-china","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=17703","title":{"rendered":"Grand Pharmaceutical Group Secures Licensing Agreement for CORXEL&#8217;s Nasal Sprays in Greater China"},"content":{"rendered":"\n<p>China-based Grand Pharmaceutical Group Co., Ltd. (<a href=\"https:\/\/www.google.com\/finance\/quote\/0512:HKG\">HKG: 0512<\/a>) has announced a significant licensing agreement with compatriot firm Corxel Pharmaceuticals (CORXEL), formerly known as Ji Xing Pharmaceuticals. The agreement grants Grand Pharma exclusive development and commercialization rights to CORXEL\u2019s OC-01 (varenicline) nasal spray and OC-02 (simpinicline) nasal spray in Greater China, which includes China mainland, Hong Kong, Macau, and Taiwan. Financial details of the deal were not disclosed.<\/p>\n\n\n\n<p><strong>OC-01 (Varenicline) Nasal Spray: A Treatment for Dry Eye and Neurotrophic Keratopathy<\/strong><br>OC-01 (varenicline) is a multi-dose, preservative-free, highly selective cholinergic agonist nasal spray under development to treat dry eye and neurotrophic keratopathy. In August 2021, CORXEL struck a licensing deal with US-headquartered Oyster Point Pharma Inc., securing exclusive development and commercialization rights to the drug in Greater China. The drug received market approval in the US in October 2021 to treat dry eye and obtained a marketing nod in China last month.<\/p>\n\n\n\n<p><strong>OC-02 (Simpinicline) Nasal Spray: A Potent Nicotinic Acetylcholine Receptor Agonist<\/strong><br>OC-02 (simpinicline) is a potent nicotinic acetylcholine receptor agonist with activities on \u03b14\u03b22, \u03b13\u03b24, \u03b13\u03b15\u03b24, and \u03b14\u03b16\u03b22 receptors, and weak excitatory activity on \u03b1 7 receptors. The drug has completed a Phase IIb study in dry eye in the US, with results showing its ability to promote tear film production, thereby improving the signs and symptoms of dry eye patients.<a href=\"https:\/\/flcube.com\">-Fineline Info &amp; Tech<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>China-based Grand Pharmaceutical Group Co., Ltd. (HKG: 0512) has announced a significant licensing agreement with&#8230;<\/p>\n","protected":false},"author":1,"featured_media":17707,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,10],"tags":[2471,683,1184,141,44,1712],"class_list":["post-17703","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","category-deals","tag-corxel-pharmaceuticals","tag-grand-pharmaceutical","tag-hkg-0512","tag-ji-xing-pharmaceuticals","tag-ophthalmology","tag-oyster-point-pharma"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Grand Pharmaceutical Group Secures Licensing Agreement for CORXEL&#039;s Nasal Sprays in Greater China - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China-based Grand Pharmaceutical Group Co., Ltd. (HKG: 0512) has announced a significant licensing agreement with compatriot firm Corxel Pharmaceuticals (CORXEL), formerly known as Ji Xing Pharmaceuticals. The agreement grants Grand Pharma exclusive development and commercialization rights to CORXEL\u2019s OC-01 (varenicline) nasal spray and OC-02 (simpinicline) nasal spray in Greater China, which includes China mainland, Hong Kong, Macau, and Taiwan. Financial details of the deal were not disclosed.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/flcube.com\/?p=17703\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Grand Pharmaceutical Group Secures Licensing Agreement for CORXEL&#039;s Nasal Sprays in Greater China\" \/>\n<meta property=\"og:description\" content=\"China-based Grand Pharmaceutical Group Co., Ltd. (HKG: 0512) has announced a significant licensing agreement with compatriot firm Corxel Pharmaceuticals (CORXEL), formerly known as Ji Xing Pharmaceuticals. The agreement grants Grand Pharma exclusive development and commercialization rights to CORXEL\u2019s OC-01 (varenicline) nasal spray and OC-02 (simpinicline) nasal spray in Greater China, which includes China mainland, Hong Kong, Macau, and Taiwan. 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