{"id":23591,"date":"2022-12-14T01:32:00","date_gmt":"2022-12-13T17:32:00","guid":{"rendered":"https:\/\/flcube.com\/?p=23591"},"modified":"2025-01-28T01:34:49","modified_gmt":"2025-01-27T17:34:49","slug":"immuneoncos-imm2520-receives-fda-clinical-trial-approval","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=23591","title":{"rendered":"ImmuneOnco&#8217;s IMM2520 Receives FDA Clinical Trial Approval"},"content":{"rendered":"\n<p>ImmuneOnco Biopharmaceuticals (Shanghai) Co., Ltd announced receiving clinical trial approval from the US FDA for its IMM2520, a bispecific antibody (BsAb) targeting CD47 and PD-L1 in solid tumors.<\/p>\n\n\n\n<p><strong>Mechanism of Action and Preclinical Results<\/strong><br>IMM2520, featuring functional IgG1 Fc, can activate macrophages and T cells simultaneously by targeting CD47 and PD-L1 in tumor cells to achieve strong synergy and induce lasting tumor-specific immune responses. The drug has demonstrated encouraging in vivo efficacy and safety in a variety of animal models.<\/p>\n\n\n\n<p><strong>Patent and Regulatory Status<\/strong><br>Previously, IMM2520, under patent protection in Japan, is under patent filing review in China, the United States, the European Union, and other regions. The drug obtained clinical trial approval in China last month.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>ImmuneOnco Biopharmaceuticals (Shanghai) Co., Ltd announced receiving clinical trial approval from the US FDA for&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[16,62,229,28,18],"class_list":["post-23591","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-cancer","tag-clinical-trial-approval-initiation","tag-immuneonco-biopharmaceuticals","tag-multi-specific-antibodies","tag-pd-1-l1"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>ImmuneOnco&#039;s IMM2520 Receives FDA Clinical Trial Approval - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"ImmuneOnco Biopharmaceuticals (Shanghai) Co., Ltd announced receiving clinical trial approval from the US FDA for its IMM2520, a bispecific antibody (BsAb) targeting CD47 and PD-L1 in solid tumors.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/flcube.com\/?p=23591\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ImmuneOnco&#039;s IMM2520 Receives FDA Clinical Trial Approval\" \/>\n<meta property=\"og:description\" content=\"Navigate the complexities of China\u2019s pharmaceutical industry with precision and clarity. 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