{"id":26172,"date":"2022-09-05T22:34:00","date_gmt":"2022-09-05T14:34:00","guid":{"rendered":"https:\/\/flcube.com\/?p=26172"},"modified":"2025-02-10T22:36:38","modified_gmt":"2025-02-10T14:36:38","slug":"bgis-stereo-seq-tech-maps-axolotl-brain-regeneration-in-world-first-study","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=26172","title":{"rendered":"BGI’s Stereo-seq Tech Maps Axolotl Brain Regeneration in World-First Study"},"content":{"rendered":"\n

China’s genomics giant BGI has revealed a landmark study using its proprietary Stereo-seq sequencing technology to construct the world’s first spatiotemporal cellular atlas of brain development and regeneration in axolotls, a species of salamander. The research, featured on the front cover of the latest Science issue, sheds light on vertebrate brain regeneration mechanisms and holds implications for regenerative medicine.<\/p>\n\n\n\n

Study Breakthroughs<\/strong>
The multi-institute team, led by BGI-Research, applied spatial enhanced resolution omics sequencing (Stereo-seq) to map single-cell transcriptomes in axolotl telencephalon sections during development and regeneration. The study identified key neural stem cell subsets driving regeneration and found parallels between regenerative and developmental processes. These insights could aid in reconstructing damaged neurons and advancing nervous system treatments.<\/p>\n\n\n\n

Research Impact<\/strong>
Dr. Ying Gu, a joint corresponding author, stated: \u201cUsing axolotls as a model, we pinpointed critical cell types in brain regeneration. This discovery offers new directions for regenerative medicine in mammals.\u201d Collaborators included institutions such as Wuhan University, the Chinese Academy of Sciences, and the University of Copenhagen.-Fineline Info & Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

China’s genomics giant BGI has revealed a landmark study using its proprietary Stereo-seq sequencing technology…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[6],"tags":[81],"class_list":["post-26172","post","type-post","status-publish","format-standard","hentry","category-rd","tag-genomics-ngs"],"yoast_head":"\nBGI's Stereo-seq Tech Maps Axolotl Brain Regeneration in World-First Study - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China's genomics giant BGI has revealed a landmark study using its proprietary Stereo-seq sequencing technology to construct the world's first spatiotemporal cellular atlas of brain development and regeneration in axolotls, a species of salamander. 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