{"id":26716,"date":"2022-08-18T09:41:00","date_gmt":"2022-08-18T01:41:00","guid":{"rendered":"https:\/\/flcube.com\/?p=26716"},"modified":"2025-02-14T18:17:41","modified_gmt":"2025-02-14T10:17:41","slug":"jemincare-licenses-oral-androgen-receptor-degrader-to-roches-genentech","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=26716","title":{"rendered":"Jemincare Licenses Oral Androgen Receptor Degrader to Roche&#8217;s Genentech"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">China-based Jiangxi Jemincare Group has entered into a licensing agreement with Swiss giant Roche&#8217;s Genentech. The deal grants Genentech exclusive global development and commercialization rights to Jemincare&#8217;s oral androgen receptor (AR) degrader, JMKX00299, including all related intellectual property rights.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Financial Terms<\/strong><br>Under the agreement, Genentech will pay a USD60 million upfront payment. It is also committed to up to USD590 million in development and commercialization milestone payments, alongside a net sales-based tiered commission.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Drug Details<\/strong><br>Androgen receptor signaling is a recognized driver of prostate cancer. JMKX00299 is designed to have therapeutic potential for patients who develop resistance to existing prostate cancer therapies, according to the press release.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Significance of the Deal<\/strong><br>This deal marks Jemincare&#8217;s third out-license project and is by far the most significant in monetary terms. Previously, Jemincare licensed a novel non-opioid drug candidate to Finnish firm Orion Corporation for rights outside China in May this year. In November 2021, it licensed a KRAS inhibitor to Huya Biosciences for ex-China development.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>China-based Jiangxi Jemincare Group has entered into a licensing agreement with Swiss giant Roche&#8217;s Genentech&#8230;.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7,10],"tags":[16,1111,1699,163],"class_list":["post-26716","post","type-post","status-publish","format-standard","hentry","category-company","category-deals","tag-cancer","tag-genentech","tag-jemincare","tag-roche"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Jemincare Licenses Oral Androgen Receptor Degrader to Roche&#039;s Genentech - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China-based Jiangxi Jemincare Group has entered into a licensing agreement with Swiss giant Roche&#039;s Genentech. 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