{"id":27781,"date":"2022-07-21T20:47:00","date_gmt":"2022-07-21T12:47:00","guid":{"rendered":"https:\/\/flcube.com\/?p=27781"},"modified":"2025-02-24T20:49:31","modified_gmt":"2025-02-24T12:49:31","slug":"livzons-v-01-and-v-01d-351-vaccines-show-strong-safety-immunity-as-covid-boosters","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=27781","title":{"rendered":"Livzon&#8217;s V-01 and V-01D-351 Vaccines Show Strong Safety, Immunity as COVID Boosters"},"content":{"rendered":"\n<p>China-based Livzon Pharmaceutical Group (<a href=\"https:\/\/www.google.com\/finance\/quote\/1513:HKG\">HKG: 1513<\/a>) released clinical data for its recombinant novel coronavirus fusion protein vaccine V-01 and bivalent vaccine V-01D-351, showing strong safety and immunogenicity as sequential booster shots. The vaccines are co-developed by Livzon subsidiary Zhuhai Livzon Monoclonal Antibodies Biotechnology and the Chinese Academy of Sciences&#8217; Institute of Biophysics.<\/p>\n\n\n\n<p><strong>Study Details<\/strong><br>The trial enrolled 77 subjects to evaluate V-01 or V-01D-351 as boosters 5-7 months after inactivated COVID-19 primary immunization. Participants included 20 in the V-01D-351 bivalent group, 38 in the V-01 group, and 19 in the inactivated vaccine group.<\/p>\n\n\n\n<p><strong>Safety and Immunogenicity<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Safety<\/strong>: Both V-01 and V-01D-351 were safe and well-tolerated, with mild-to-moderate adverse reactions and no serious events.<\/li>\n\n\n\n<li><strong>Immunogenicity<\/strong>: Heterologous boosting with V-01 or V-01D-351 induced stronger humoral responses than inactivated vaccine boosters. The V-01D-351 bivalent booster showed the highest neutralizing antibody titers against SARS-CoV-2 prototype, Delta, and Omicron BA.1 strains at Day 14. Titers remained elevated 90 days post-inoculation.<\/li>\n<\/ul>\n\n\n\n<p><strong>Vaccine Design and Future Plans<\/strong><br>The vaccines&#8217; unique molecular design enhances humoral and cellular immunity, offering robust protection against Omicron variants. V-01, filed for emergency sequential use, awaits regulatory decisions in China and is prepared for international submissions.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>China-based Livzon Pharmaceutical Group (HKG: 1513) released clinical data for its recombinant novel coronavirus fusion&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[17,13,1228,457,12],"class_list":["post-27781","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-clinical-trial-results","tag-covid-19","tag-hkg-1513","tag-livzon-pharmaceutical","tag-vaccine"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Livzon&#039;s V-01 and V-01D-351 Vaccines Show Strong Safety, Immunity as COVID Boosters - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China-based Livzon Pharmaceutical Group (HKG: 1513) released clinical data for its recombinant novel coronavirus fusion protein vaccine V-01 and bivalent vaccine V-01D-351, showing strong safety and immunogenicity as sequential booster shots. 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