{"id":28556,"date":"2022-07-04T18:26:00","date_gmt":"2022-07-04T10:26:00","guid":{"rendered":"https:\/\/flcube.com\/?p=28556"},"modified":"2025-03-03T18:31:40","modified_gmt":"2025-03-03T10:31:40","slug":"fosun-pharmaceutical-and-reneuron-renew-ctx-cell-therapy-deal-for-china","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=28556","title":{"rendered":"Fosun Pharmaceutical and ReNeuron Renew CTX Cell Therapy Deal for China"},"content":{"rendered":"\n<p>China-based Shanghai Fosun Pharmaceutical (Group) Co., Ltd (<a href=\"https:\/\/www.google.com\/finance\/quote\/600196:SHA\">SHA: 600196<\/a>, <a href=\"https:\/\/www.google.com\/finance\/quote\/2196:HKG\">HKG: 2196<\/a>) has negotiated a new &#8220;supplemental terms agreement&#8221; with UK-based partner ReNeuron Group plc (<a href=\"https:\/\/www.google.com\/finance\/quote\/RNUGF:OTCMKTS\">OTCMKTS: RNUGF<\/a>) worth GBP 6 million (USD 7.3 million). This deal builds on an earlier agreement signed in April 2019, under which Fosun obtained exclusive development, manufacturing, and commercialization rights in China to ReNeuron\u2019s off-the-shelf stem-cell therapy programs. The latest renewal will lead to the technology transfer of ReNeuron\u2019s CTX cell therapy for recovering stroke patients to Fosun for local manufacturing.<\/p>\n\n\n\n<p><strong>Deal Terms<\/strong><br>Under the deal terms, Fosun will pay GBP 1 million upfront within 24 months, including a GBP 320,000 (USD 387,676) down-payment made in January this year, to cover the initial supply of CTX cell bank vials and services for technology transfer. The remaining GBP 5 million (USD 6 million) will be paid over the medium to longer term for ReNeuron to continue providing CTX cell bank vials to Fosun.<\/p>\n\n\n\n<p><strong>Manufacturing Facility<\/strong><br>Fosun is reportedly set to establish a dedicated 20,000-square-foot GMP facility to manufacture the CTX products in Pudong, Shanghai, expected to be operational by Q1, 2023. This will enable later-stage clinical and commercial use of CTX in Greater China and allow Fosun to explore more clinical uses for CTX in neurological diseases.<\/p>\n\n\n\n<p><strong>CTX Cell Therapy<\/strong><br>ReNeuron\u2019s CTX stem cell therapy candidate consists of a neural stem cell line generated using the UK firm\u2019s cell expansion and selection technologies before full-scale manufacturing. This results in a cryopreserved, clinical, and commercial-grade cell therapy product capable of treating patients who have suffered an ischemic stroke and are in the recovery \/ rehabilitative stage. In the Phase IIa PISCES II study, the therapy produced a response rate of 35% in 23 enrolled subjects, indicating a clinically meaningful improvement in the level of disability after 12 months.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>China-based Shanghai Fosun Pharmaceutical (Group) Co., Ltd (SHA: 600196, HKG: 2196) has negotiated a new&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,10],"tags":[77,159,893,3804,3803,892],"class_list":["post-28556","post","type-post","status-publish","format-standard","hentry","category-company","category-deals","tag-cell-therapy","tag-fosun-pharmaceutical","tag-hkg-2196","tag-otcmkts-rnugf","tag-reneuron","tag-sha-600196"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Fosun Pharmaceutical and ReNeuron Renew CTX Cell Therapy Deal for China - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China-based Shanghai Fosun Pharmaceutical (Group) Co., Ltd (SHA: 600196, HKG: 2196) has negotiated a new &quot;supplemental terms agreement&quot; with UK-based partner ReNeuron Group plc (OTCMKTS: RNUGF) worth GBP 6 million (USD 7.3 million). This deal builds on an earlier agreement signed in April 2019, under which Fosun obtained exclusive development, manufacturing, and commercialization rights in China to ReNeuron\u2019s off-the-shelf stem-cell therapy programs. The latest renewal will lead to the technology transfer of ReNeuron\u2019s CTX cell therapy for recovering stroke patients to Fosun for local manufacturing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/flcube.com\/?p=28556\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fosun Pharmaceutical and ReNeuron Renew CTX Cell Therapy Deal for China\" \/>\n<meta property=\"og:description\" content=\"Navigate the complexities of China\u2019s pharmaceutical industry with precision and clarity. 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