{"id":28584,"date":"2022-07-04T18:57:00","date_gmt":"2022-07-04T10:57:00","guid":{"rendered":"https:\/\/flcube.com\/?p=28584"},"modified":"2025-03-03T18:59:28","modified_gmt":"2025-03-03T10:59:28","slug":"brii-biosciences-exercises-option-for-vir-3434-in-greater-china","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=28584","title":{"rendered":"Brii Biosciences Exercises Option for VIR-3434 in Greater China"},"content":{"rendered":"\n<p>China-based Brii Biosciences Limited (<a href=\"https:\/\/www.google.com\/finance\/quote\/2137:HKG\">HKG: 2137<\/a>) announced the exercise of its option to acquire exclusive development and commercialization rights for VIR-3434 (BRII-877) in Greater China as part of its broader collaboration with Vir Biotechnology, Inc. (<a href=\"https:\/\/www.google.com\/finance\/quote\/VIR:NASDAQ\">NASDAQ: VIR<\/a>).<\/p>\n\n\n\n<p><strong>Drug Profile<\/strong><br>VIR-3434, an investigational subcutaneously administered HBV-neutralizing monoclonal antibody, is designed to block the entry of all 10 genotypes of HBV into hepatocytes and reduce the level of virions and subviral particles in the blood. The drug is currently in Phase II development. This acquisition adds to Brii Bio\u2019s leading clinical pipeline for hepatitis B virus (HBV) and provides potential combination treatment options aimed at developing a functional cure for HBV.<\/p>\n\n\n\n<p><strong>Collaboration Background<\/strong><br>In May 2018, Brii Bio entered into a collaboration, option, and license agreement with Vir, granting Brii Bio the option to acquire exclusive rights to certain Vir programs in Greater China. In June 2020, Brii Bio exercised its option for BRII-835 (VIR-2218). Under the current agreement, Brii Bio will pay an option exercise fee, regulatory and commercial milestone payments, and tiered royalty payments based on net sales for VIR-3434 (BRII-877). The company retains two pending licensing options.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>China-based Brii Biosciences Limited (HKG: 2137) announced the exercise of its option to acquire exclusive&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,10,11],"tags":[449,631,1219,1542,792],"class_list":["post-28584","post","type-post","status-publish","format-standard","hentry","category-company","category-deals","category-drug","tag-brii-biosciences","tag-hiv-aids-care","tag-hkg-2137","tag-nasdaq-vir","tag-vir-biotechnology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Brii Biosciences Exercises Option for VIR-3434 in Greater China - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China-based Brii Biosciences Limited (HKG: 2137) announced the exercise of its option to acquire exclusive development and commercialization rights for VIR-3434 (BRII-877) in Greater China as part of its broader collaboration with Vir Biotechnology, Inc. 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