{"id":3156,"date":"2024-06-11T11:13:08","date_gmt":"2024-06-11T03:13:08","guid":{"rendered":"https:\/\/flcube.com\/?p=3156"},"modified":"2024-10-18T12:49:49","modified_gmt":"2024-10-18T04:49:49","slug":"biosions-bosakitug-shows-positive-results-in-atopic-dermatitis-phase-ii-poc-study","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=3156","title":{"rendered":"Biosion\u2019s Bosakitug Shows Positive Results in Atopic Dermatitis Phase II POC Study"},"content":{"rendered":"\n<p>Biosion, a clinical-stage biotechnology company with operations in Delaware, U.S., and China, has announced key findings from its Phase II proof-of-concept (POC) ADAMANT study for bosakitug, a candidate in its pipeline for the treatment of atopic dermatitis (AD). Bosakitug is a monoclonal antibody (mAb) that targets thymic stromal lymphopoietin (TSLP), a cytokine that plays a significant role in the pathogenesis of AD, asthma, and other eosinophil and Th2 immune-related diseases.<\/p>\n\n\n\n<p>The study protocol involved all subjects receiving a weekly induction dose of 300mg for the initial 4 weeks, followed by maintenance doses of 300mg every two weeks, totaling 10 administrations. The results were impressive, with 94%, 69%, and 25% of participants achieving EASI (Eczema Area and Severity Index) scores of 75, 90, and 100, respectively, at 25 weeks (indicating a minimum 75%, 90%, or 100% improvement from baseline). Additionally, the investigator global assessment (IGA) score of 0\/1, which signifies complete or near-complete clearance of lesions, was achieved by 94% of the participants. All subjects maintained an EASI 75 compliance even 12 weeks after their final administration.- <a href=\"https:\/\/flcube.com\">Flcube.com<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biosion, a clinical-stage biotechnology company with operations in Delaware, U.S., and China, has announced key&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[65,694,17],"class_list":["post-3156","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-auto-immune","tag-biosion","tag-clinical-trial-results"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Biosion\u2019s Bosakitug Shows Positive Results in Atopic Dermatitis Phase II POC Study - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Biosion, a clinical-stage biotechnology company with operations in Delaware, U.S., and China, has announced key findings from its Phase II proof-of-concept (POC) ADAMANT study for bosakitug, a candidate in its pipeline for the treatment of atopic dermatitis (AD). 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