{"id":33585,"date":"2025-05-16T12:28:02","date_gmt":"2025-05-16T04:28:02","guid":{"rendered":"https:\/\/flcube.com\/?p=33585"},"modified":"2025-05-16T12:28:03","modified_gmt":"2025-05-16T04:28:03","slug":"haisco-pharmas-hsk21542-approved-by-nmpa-for-post-abdominal-surgery-pain","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=33585","title":{"rendered":"Haisco Pharma’s HSK21542 Approved by NMPA for Post-Abdominal Surgery Pain"},"content":{"rendered":"\n

Haisco Pharmaceutical Group Co., Ltd (SHE: 002653<\/a>) has announced that it has received marketing approval from the National Medical Products Administration (NMPA) for its Category 1 drug HSK21542, indicated for mild to moderate pain following abdominal surgery.<\/p>\n\n\n\n

HSK21542: Mechanism and Benefits<\/strong>
HSK21542 is a selective peripheral Kappa receptor agonist characterized by high selectivity and affinity. It works by synergistically regulating potassium and calcium currents with the participation of G protein. The drug inhibits itching by blocking the transmission of itching signals and reduces the excitability of the dorsal root ganglion and peripheral sensory nerves. This action decreases the release of inflammatory factors and neurotransmitters. Importantly, HSK21542 does not cross the blood-brain barrier, allowing it to provide peripheral analgesic and anti-itch effects while avoiding central opioid-related side effects such as hallucinations, addiction, and respiratory depression.-Fineline Info & Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Haisco Pharmaceutical Group Co., Ltd (SHE: 002653) has announced that it has received marketing approval…<\/p>\n","protected":false},"author":1,"featured_media":33586,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7,11],"tags":[139,15,929],"class_list":["post-33585","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","category-drug","tag-haisco-pharmaceutical","tag-product-approvals","tag-she-002653"],"yoast_head":"\nHaisco Pharma's HSK21542 Approved by NMPA for Post-Abdominal Surgery Pain - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Haisco Pharmaceutical Group Co., Ltd (SHE: 002653) has announced that it has received marketing approval from the National Medical Products Administration (NMPA) for its Category 1 drug HSK21542, indicated for mild to moderate pain following abdominal surgery.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/flcube.com\/?p=33585\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Haisco Pharma's HSK21542 Approved by NMPA for Post-Abdominal Surgery Pain\" \/>\n<meta property=\"og:description\" content=\"Haisco Pharmaceutical Group Co., Ltd (SHE: 002653) has announced that it has received marketing approval from the National Medical Products Administration (NMPA) for its Category 1 drug HSK21542, indicated for mild to moderate pain following abdominal surgery.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/flcube.com\/?p=33585\" \/>\n<meta property=\"og:site_name\" content=\"Insight, China's Pharmaceutical Industry\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/profile.php?id=61566606313834\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-16T04:28:02+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-16T04:28:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/flcube.com\/wp-content\/uploads\/2025\/05\/1605.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"608\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Fineline Cube\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:description\" content=\"Navigate the complexities of China\u2019s pharmaceutical industry with precision and clarity. 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