{"id":34484,"date":"2025-05-30T16:29:23","date_gmt":"2025-05-30T08:29:23","guid":{"rendered":"https:\/\/flcube.com\/?p=34484"},"modified":"2025-05-30T16:29:25","modified_gmt":"2025-05-30T08:29:25","slug":"innovent-biologics-doses-first-patient-in-phase-iii-psoriasis-trial-for-picankibart","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=34484","title":{"rendered":"Innovent Biologics Doses First Patient in Phase III Psoriasis Trial for Picankibart"},"content":{"rendered":"\n<p>China-based Innovent Biologics, Inc. (<a href=\"https:\/\/www.google.com\/finance\/quote\/1801:HKG\">HKG: 1801<\/a>) announced the first subject dosing in a Phase III clinical study for picankibart, a recombinant anti-interleukin 23p19 subunit (IL-23p19) antibody. The trial aims to evaluate the efficacy and safety of picankibart in psoriasis patients who have not responded adequately to anti-IL-17 antibodies. The study is expected to enroll 310 subjects and includes a control group continuing to receive IL-17 inhibitors. The primary endpoint is the proportion of participants achieving a static Physician&#8217;s Global Assessment (sPGA) score of clear (0) or almost clear (1) at week 16.<\/p>\n\n\n\n<p><strong>Picankibart&#8217;s Promising Phase II Results<\/strong><br>Picankibart (IBI112), a monoclonal antibody specifically targeting the IL-23p19 subunit, has demonstrated its ability to rapidly take effect and improve quality of life in patients with a poor response to previous treatments. In earlier Phase II trials, the drug showed significant promise in addressing unmet needs for patients with inadequate response to existing therapies.<\/p>\n\n\n\n<p><strong>Regulatory Progress in China<\/strong><br>Picankibart is currently awaiting regulatory decisions in China for the treatment of moderate-to-severe plaque psoriasis. In September of last year, the National Medical Products Administration (NMPA) accepted the New Drug Application (NDA) for review, marking a significant step toward potential approval in the Chinese market.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>China-based Innovent Biologics, Inc. (HKG: 1801) announced the first subject dosing in a Phase III&#8230;<\/p>\n","protected":false},"author":1,"featured_media":34485,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[17,910,198],"class_list":["post-34484","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","category-drug","tag-clinical-trial-results","tag-hkg-1801","tag-innovent-biologics"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Innovent Biologics Doses First Patient in Phase III Psoriasis Trial for Picankibart - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China-based Innovent Biologics, Inc. (HKG: 1801) announced the first subject dosing in a Phase III clinical study for picankibart, a recombinant anti-interleukin 23p19 subunit (IL-23p19) antibody. The trial aims to evaluate the efficacy and safety of picankibart in psoriasis patients who have not responded adequately to anti-IL-17 antibodies. The study is expected to enroll 310 subjects and includes a control group continuing to receive IL-17 inhibitors. The primary endpoint is the proportion of participants achieving a static Physician&#039;s Global Assessment (sPGA) score of clear (0) or almost clear (1) at week 16.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/flcube.com\/?p=34484\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Innovent Biologics Doses First Patient in Phase III Psoriasis Trial for Picankibart\" \/>\n<meta property=\"og:description\" content=\"China-based Innovent Biologics, Inc. (HKG: 1801) announced the first subject dosing in a Phase III clinical study for picankibart, a recombinant anti-interleukin 23p19 subunit (IL-23p19) antibody. The trial aims to evaluate the efficacy and safety of picankibart in psoriasis patients who have not responded adequately to anti-IL-17 antibodies. The study is expected to enroll 310 subjects and includes a control group continuing to receive IL-17 inhibitors. 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