{"id":34777,"date":"2025-06-05T17:58:24","date_gmt":"2025-06-05T09:58:24","guid":{"rendered":"https:\/\/flcube.com\/?p=34777"},"modified":"2025-06-05T17:58:25","modified_gmt":"2025-06-05T09:58:25","slug":"biocytogen-and-chia-tai-tianqing-win-nmpa-approval-for-ntb003-clinical-trials","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=34777","title":{"rendered":"Biocytogen and Chia Tai Tianqing Win NMPA Approval for NTB003 Clinical Trials"},"content":{"rendered":"\n

Chinese partners Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (HKG: 2315<\/a>) and Chia Tai Tianqing announced that they have received clinical approval from the National Medical Products Administration (NMPA) for their co-developed NTB003 (BCG009), a second-generation anti-IGF-1R antibody. The drug is intended for the treatment of thyroid eye disease (TED).<\/p>\n\n\n\n

NTB003 Development and Advantages<\/strong>
NTB003 was discovered and optimized using Biocytogen\u2019s proprietary RenMab platform. Chia Tai Tianqing led the CMC process development, GLP safety evaluation, and IND registration. Compared to first-generation approved drugs, NTB003 shows improvements in molecular affinity, druggability, and half-life. It has demonstrated potent signal-blocking effects in vitro and can effectively inhibit hyaluronic acid (HA) release.<\/p>\n\n\n\n

Collaboration and Next Steps<\/strong>
Chia Tai Tianqing will accelerate clinical trials and commercialization in China. Biocytogen will lead overseas licensing and partnership efforts for NTB003.-Fineline Info & Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Chinese partners Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (HKG: 2315) and Chia Tai Tianqing announced that…<\/p>\n","protected":false},"author":1,"featured_media":34778,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[2372,661,62,1214,44],"class_list":["post-34777","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","category-drug","tag-biocytogen-boston","tag-chia-tai-tianqing-pharmaceutical","tag-clinical-trial-approval-initiation","tag-hkg-2315","tag-ophthalmology"],"yoast_head":"\nBiocytogen and Chia Tai Tianqing Win NMPA Approval for NTB003 Clinical Trials - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Chinese partners Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (HKG: 2315) and Chia Tai Tianqing announced that they have received clinical approval from the National Medical Products Administration (NMPA) for their co-developed NTB003 (BCG009), a second-generation anti-IGF-1R antibody. The drug is intended for the treatment of thyroid eye disease (TED).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/flcube.com\/?p=34777\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biocytogen and Chia Tai Tianqing Win NMPA Approval for NTB003 Clinical Trials\" \/>\n<meta property=\"og:description\" content=\"Chinese partners Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (HKG: 2315) and Chia Tai Tianqing announced that they have received clinical approval from the National Medical Products Administration (NMPA) for their co-developed NTB003 (BCG009), a second-generation anti-IGF-1R antibody. 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