{"id":34981,"date":"2025-06-10T17:33:15","date_gmt":"2025-06-10T09:33:15","guid":{"rendered":"https:\/\/flcube.com\/?p=34981"},"modified":"2025-06-10T17:33:16","modified_gmt":"2025-06-10T09:33:16","slug":"hengrui-pharmaceuticals-launches-aiweida-for-her2-mutated-nsclc-in-china","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=34981","title":{"rendered":"Hengrui Pharmaceuticals Launches Aiweida for HER2-Mutated NSCLC in China"},"content":{"rendered":"\n

China’s Jiangsu Hengrui Pharmaceuticals Co., Ltd. (SHA: 600276<\/a>) announced the first commercial shipment of its self-developed Class 1 innovative drug Aiweida (trastuzumab rezetecan), marking the official market launch of the HER2-targeted antibody-drug conjugate (ADC).<\/p>\n\n\n\n

Drug Approval and Indication<\/strong>
Trastuzumab rezetecan, developed independently by Hengrui, received approval in China last month. It is indicated for the treatment of adult patients with unresectable locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring HER2 (ERBB2) activating mutations who have previously received at least one systemic therapy.<\/p>\n\n\n\n

Clinical Trial Results<\/strong>
The approval was primarily based on the HORIZON-Lung study, which demonstrated an objective response rate (ORR) of 74.5% and a median progression-free survival (mPFS) of 11.5 months, with a 12-month PFS rate of 48.6% in previously treated HER2-mutated advanced or metastatic NSCLC patients.-Fineline Info & Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

China’s Jiangsu Hengrui Pharmaceuticals Co., Ltd. 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