{"id":35505,"date":"2025-06-18T21:28:41","date_gmt":"2025-06-18T13:28:41","guid":{"rendered":"https:\/\/flcube.com\/?p=35505"},"modified":"2025-06-18T21:28:42","modified_gmt":"2025-06-18T13:28:42","slug":"clover-biopharmaceuticals-completes-enrollment-for-phase-i-trial-of-rsv-hmpv-combination-vaccines","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=35505","title":{"rendered":"Clover Biopharmaceuticals Completes Enrollment for Phase I Trial of RSV + hMPV Combination Vaccines"},"content":{"rendered":"\n

China-based Clover Biopharmaceuticals Ltd., (HKG: 2197<\/a>) announced the completion of enrollment for the first participants in a Phase I clinical trial evaluating its SCB-1022 (RSV + hMPV) and SCB-1033 (RSV + hMPV + PIV3) respiratory combination vaccine candidates. These candidates were developed using the company\u2019s proprietary Trimer-Tag vaccine platform.<\/p>\n\n\n\n

Trial Details<\/strong>
The trial primarily assesses the safety, reactogenicity, and immunogenicity of the vaccines. It has recruited 192 elderly participants aged 60\u201385, who will be randomly administered SCB-1022 (RSV + hMPV), SCB-1033 (RSV + hMPV + PIV3), or the control vaccine SCB-1019 (RSV).<\/p>\n\n\n\n

Previous Results<\/strong>
In October 2024, Clover Bio released Phase I clinical trial results for its unadjuvanted RSV PreF candidate vaccine (SCB-1019) in 70 elderly participants aged 60\u201385. A head-to-head comparison with GSK\u2019s AS01E-adjuvanted RSV vaccine, Arexyv, showed that SCB-1019 demonstrated potentially best-in-class immunogenicity and tolerability profiles.-Fineline Info & Tech<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

China-based Clover Biopharmaceuticals Ltd., (HKG: 2197) announced the completion of enrollment for the first participants…<\/p>\n","protected":false},"author":1,"featured_media":35506,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[62,651,1123,12],"class_list":["post-35505","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","category-drug","tag-clinical-trial-approval-initiation","tag-clover-biopharmaceuticals","tag-hkg-2197","tag-vaccine"],"yoast_head":"\nClover Biopharmaceuticals Completes Enrollment for Phase I Trial of RSV + hMPV Combination Vaccines - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China-based Clover Biopharmaceuticals Ltd., (HKG: 2197) announced the completion of enrollment for the first participants in a Phase I clinical trial evaluating its SCB-1022 (RSV + hMPV) and SCB-1033 (RSV + hMPV + PIV3) respiratory combination vaccine candidates. 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