{"id":40290,"date":"2025-08-28T15:01:35","date_gmt":"2025-08-28T07:01:35","guid":{"rendered":"https:\/\/flcube.com\/?p=40290"},"modified":"2025-08-28T15:01:35","modified_gmt":"2025-08-28T07:01:35","slug":"anglikang-secures-exclusive-rights-to-yafeis-imd%e2%80%911005-in-china","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=40290","title":{"rendered":"Anglikang Secures Exclusive Rights to Yafei\u2019s IMD\u20111005 in China"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Zhejiang Anglikang Pharmaceutical Co., Ltd. (<a href=\"https:\/\/www.google.com\/finance\/quote\/002940:SHE\">SHE: 002940<\/a>) announced that it has entered into a <strong>license agreement<\/strong> with <strong>Yafei (Shanghai) Biomedical Technology Co., Ltd.<\/strong> and its subsidiary <strong>Affinity Biopharmaceutical Co., Ltd.<\/strong> The agreement grants Anglikang exclusive rights to <strong>research, develop, manufacture and commercialise<\/strong> the <strong>IMD\u20111005<\/strong> TMEAbody in China, including <strong>mainland, Hong\u202fKong, Macau and Taiwan<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-deal-highlights\">Deal Highlights<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Item<\/th><th>Detail<\/th><\/tr><\/thead><tbody><tr><td><strong>License Scope<\/strong><\/td><td>Exclusive R&amp;D, production &amp; commercialization of <strong>IMD\u20111005<\/strong> in China<\/td><\/tr><tr><td><strong>Upfront Payment<\/strong><\/td><td><strong>RMB\u202f150\u202fmillion<\/strong> paid in staged instalments to Yafei &amp; Affinity<\/td><\/tr><tr><td><strong>Milestone Payments<\/strong><\/td><td>Up to <strong>RMB\u202f620\u202fmillion<\/strong> tied to R&amp;D and sales milestones<\/td><\/tr><tr><td><strong>Royalty<\/strong><\/td><td><strong>12.8\u202f%<\/strong> of net sales during the royalty period<\/td><\/tr><tr><td><strong>Target<\/strong><\/td><td><strong>CD47\u2011targeting Tumour Micro\u2011Environment\u2011Activated Antibody (TMEAbody)<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-about-imd-1005\">About IMD\u20111005<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mechanism<\/strong> \u2013 Blocks CD47, a key \u201cdon\u2019t\u2011eat\u2011me\u201d signal, to enhance macrophage\u2011mediated tumour clearance.<\/li>\n\n\n\n<li><strong>Innovation<\/strong> \u2013 First\u2011in\u2011class TMEAbody designed to activate within the tumour micro\u2011environment.<\/li>\n\n\n\n<li><strong>Global Position<\/strong> \u2013 Developed by Affinity, a Yafei subsidiary, and the only CD47\u2011targeting TMEAbody currently in advanced clinical development.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-strategic-implications\">Strategic Implications<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Market Expansion<\/strong> \u2013 Anglikang will be the sole manufacturer and distributor of IMD\u20111005 across the Chinese market, positioning it as a leader in oncology therapeutics.<\/li>\n\n\n\n<li><strong>Financial Upside<\/strong> \u2013 The RMB\u202f620\u202fM milestone budget and 12.8\u202f% royalty structure provide a robust revenue pipeline once the product moves to market.<\/li>\n\n\n\n<li><strong>Collaborative Synergy<\/strong> \u2013 The partnership leverages Yafei\u2019s global R&amp;D capabilities and Affinity\u2019s clinical expertise, enhancing Anglikang\u2019s product portfolio and pipeline depth.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-outlook\">Outlook<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Anglikang plans to initiate pre\u2011clinical studies immediately under the new license, with a projected regulatory filing in 2027. The company\u2019s management remains optimistic about the commercial prospects of IMD\u20111005, citing its unique mechanism and the strong demand for CD47\u2011targeted therapies in China\u2019s rapidly growing oncology market.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/flcube.com\/wp-content\/uploads\/2025\/08\/\u6602\u5229\u5eb7\uff1a\u5173\u4e8e\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u4e4b\u6388\u6743\u8bb8\u53ef\u534f\u8bae\u7684\u516c\u544a.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of \u6602\u5229\u5eb7\uff1a\u5173\u4e8e\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u4e4b\u6388\u6743\u8bb8\u53ef\u534f\u8bae\u7684\u516c\u544a.\"><\/object><a id=\"wp-block-file--media-2d83f2be-2ac4-4ee8-9cd7-087ff061ca7e\" href=\"https:\/\/flcube.com\/wp-content\/uploads\/2025\/08\/\u6602\u5229\u5eb7\uff1a\u5173\u4e8e\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u4e4b\u6388\u6743\u8bb8\u53ef\u534f\u8bae\u7684\u516c\u544a.pdf\">\u6602\u5229\u5eb7\uff1a\u5173\u4e8e\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u4e4b\u6388\u6743\u8bb8\u53ef\u534f\u8bae\u7684\u516c\u544a<\/a><a href=\"https:\/\/flcube.com\/wp-content\/uploads\/2025\/08\/\u6602\u5229\u5eb7\uff1a\u5173\u4e8e\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u4e4b\u6388\u6743\u8bb8\u53ef\u534f\u8bae\u7684\u516c\u544a.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-2d83f2be-2ac4-4ee8-9cd7-087ff061ca7e\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Zhejiang Anglikang Pharmaceutical Co., Ltd. (SHE: 002940) announced that it has entered into a license&#8230;<\/p>\n","protected":false},"author":1,"featured_media":40292,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7,10],"tags":[2553,1539,16,1538,4319],"class_list":["post-40290","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","category-deals","tag-affinity-biopharmaceutical","tag-anglikang-pharmaceutical","tag-cancer","tag-she-002940","tag-yafei-biomedical-technology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Anglikang Secures Exclusive Rights to Yafei\u2019s IMD\u20111005 in China - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Zhejiang Anglikang Pharmaceutical (SHE: 002940) has signed a license agreement with Yafei (Shanghai) Biomedical Technology and Affinity Biopharmaceutical, granting exclusive research, production and commercial rights for the CD47\u2011targeting TMEAbody IMD\u20111005 across mainland China, Hong\u202fKong, Macau and Taiwan. 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