{"id":4404,"date":"2024-10-08T15:42:40","date_gmt":"2024-10-08T07:42:40","guid":{"rendered":"https:\/\/flcube.com\/?p=4404"},"modified":"2024-10-24T23:19:59","modified_gmt":"2024-10-24T15:19:59","slug":"regor-therapeutics-strikes-deal-with-genentech-for-cdk-inhibitors-fetching-usd-850-million-upfront","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=4404","title":{"rendered":"Regor Therapeutics Strikes Deal with Genentech for CDK Inhibitors, Fetching USD 850 Million Upfront"},"content":{"rendered":"\n

Regor Therapeutics Group, a US-based biotech with significant ties to China, has entered into a licensing agreement with Genentech, a subsidiary of Swiss pharmaceutical giant Roche (SWX: ROG<\/a>; OTCMKTS: RHHBY<\/a>) . Under the agreement, Genentech will acquire the rights to develop, manufacture, and commercialize Regor’s next-generation CDK inhibitors, including the Phase I candidate RGT-419B for the treatment of breast cancer, for an upfront payment of USD 850 million. The deal also includes potential future payments based on undisclosed milestones .<\/p>\n\n\n\n

RGT-419B is designed to be a potent CDK4 inhibitor with additional activity against CDK2 and selectivity against CDK6, which may overcome resistance and reduce hematologic toxicity. The molecule has shown promising results in Phase I trials, with a favorable safety profile and preliminary signs of efficacy as a monotherapy in patients with advanced breast cancer who have failed prior CDK4\/6 inhibitor treatments .<\/p>\n\n\n\n

Regor, which operates out of Boston, Massachusetts, and Shanghai, China, was founded in July 2018 with Series A funding from Qilu Pharmaceutical Group. The company’s pipeline includes innovative drug candidates in oncology, metabolism, and auto-immunity, with RGT-419B at the forefront of its oncology programs .- Flcube.com<\/a><\/p>\n\n\n\n

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Regor Therapeutics Group, a US-based biotech with significant ties to China, has entered into a…<\/p>\n","protected":false},"author":1,"featured_media":4405,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,10],"tags":[940,954,163,939],"class_list":["post-4404","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","category-deals","tag-otcmkts-rhhby","tag-regor-therapeutics","tag-roche","tag-swx-rop"],"yoast_head":"\nRegor Therapeutics Strikes Deal with Genentech for CDK Inhibitors, Fetching USD 850 Million Upfront - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Regor Therapeutics Group, a US-based biotech with significant ties to China, has entered into a licensing agreement with Genentech, a subsidiary of Swiss pharmaceutical giant Roche (SWX: ROG; OTCMKTS: RHHBY) . 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