{"id":56838,"date":"2026-02-11T00:31:29","date_gmt":"2026-02-10T16:31:29","guid":{"rendered":"https:\/\/flcube.com\/?p=56838"},"modified":"2026-02-11T00:31:30","modified_gmt":"2026-02-10T16:31:30","slug":"china-resources-pharma-to-divest-17-87-stake-in-tianmai-bio-for-205-million","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=56838","title":{"rendered":"China Resources Pharma to Divest 17.87% Stake in Tianmai Bio for $205 Million"},"content":{"rendered":"\n<p><strong>China Resources Pharmaceutical Group Co., Ltd.<\/strong> (<strong><a href=\"https:\/\/www.google.com\/finance\/quote\/3320:HKG\">HKG:\u202f3320<\/a><\/strong>) announced plans to <strong>sell a 17.87% stake<\/strong> in <strong>Hefei Tianmai Biotechnology Co., Ltd.<\/strong>, with a <strong>minimum listing price of RMB\u202f1.42 billion (USD\u202f205 million)<\/strong>. The divestment follows <strong>ORMD-0801&#8217;s failed NMPA approval<\/strong> in December\u202f2025, prompting CR Pharma to <strong>further reduce exposure<\/strong> to the insulin-focused biopharmaceutical company after <strong>multiple stake adjustments since 2016<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-transaction-overview\">Transaction Overview<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Element<\/th><th>Detail<\/th><\/tr><\/thead><tbody><tr><td><strong>Seller<\/strong><\/td><td>China Resources Pharmaceutical Group (HKG:\u202f3320)<\/td><\/tr><tr><td><strong>Asset<\/strong><\/td><td>17.87% stake in Hefei Tianmai Biotechnology Co., Ltd.<\/td><\/tr><tr><td><strong>Minimum Price<\/strong><\/td><td><strong>RMB\u202f1.42 billion (USD\u202f205 million)<\/strong><\/td><\/tr><tr><td><strong>Valuation Method<\/strong><\/td><td>Open listing\/auction<\/td><\/tr><tr><td><strong>Tianmai Bio Focus<\/strong><\/td><td>Recombinant human insulin R&amp;D, production, and sales<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-shareholding-history-amp-strategic-evolution\">Shareholding History &amp; Strategic Evolution<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Timeline<\/th><th>Event<\/th><th>CR Pharma Stake<\/th><th>Strategic Context<\/th><\/tr><\/thead><tbody><tr><td><strong>2010<\/strong><\/td><td>Tianmai Bio founded<\/td><td>\u2013<\/td><td>Insulin manufacturing focus<\/td><\/tr><tr><td><strong>Nov\u202f2016<\/strong><\/td><td>CR Pharma initial investment<\/td><td><strong>20%<\/strong><\/td><td>Entry into diabetes biopharma<\/td><\/tr><tr><td><strong>Dec\u202f2017<\/strong><\/td><td>GMP certification delay; partial exit<\/td><td>Sold <strong>14.12%<\/strong> at HKD\u202f1.147B (USD\u202f146M)<\/td><td>Risk management; retained 5.88%<\/td><\/tr><tr><td><strong>2020<\/strong><\/td><td>Increased stake<\/td><td><strong>23.75%<\/strong> (largest shareholder)<\/td><td>Recommitment to insulin + ORMD-0801 oral insulin potential<\/td><\/tr><tr><td><strong>Dec\u202f2025<\/strong><\/td><td>ORMD-0801 NMPA rejection<\/td><td><strong>23.75%<\/strong> maintained until now<\/td><td>Catalyst for full exit strategy<\/td><\/tr><tr><td><strong>Feb\u202f2026<\/strong><\/td><td>Planned divestment of 17.87%<\/td><td>Reducing to <strong>~5.88%<\/strong><\/td><td>Monetization of remaining position<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-ormd-0801-failure-amp-investment-thesis-breakdown\">ORMD-0801 Failure &amp; Investment Thesis Breakdown<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Parameter<\/th><th>ORMD-0801 Profile<\/th><th>Failure Impact<\/th><\/tr><\/thead><tbody><tr><td><strong>Technology<\/strong><\/td><td><strong>Recombinant human insulin enteric-coated capsule<\/strong> (oral insulin)<\/td><td>Revolutionary potential vs. injectable insulin<\/td><\/tr><tr><td><strong>Origin<\/strong><\/td><td>Licensed from <strong>Israel&#8217;s Oramed Pharma<\/strong><\/td><td>Technology transfer and China-specific development costs<\/td><\/tr><tr><td><strong>NMPA Status<\/strong><\/td><td><strong>Rejected December\u202f2025<\/strong><\/td><td>Core value driver eliminated; Tianmai Bio reduced to injectable insulin commodity player<\/td><\/tr><tr><td><strong>CR Pharma Response<\/strong><\/td><td><strong>Accelerated divestment<\/strong><\/td><td>Loss of confidence in Tianmai Bio growth trajectory; capital reallocation to higher-priority assets<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-market-context-amp-strategic-implications\">Market Context &amp; Strategic Implications<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Factor<\/th><th>Strategic Analysis<\/th><\/tr><\/thead><tbody><tr><td><strong>China Insulin Market<\/strong><\/td><td><strong>&gt;100 million diabetes patients<\/strong>; intense price competition from domestic (Gan &amp; Lee, Tonghua Dongbao) and multinational (Novo Nordisk, Sanofi) manufacturers<\/td><\/tr><tr><td><strong>Tianmai Bio Position<\/strong><\/td><td>Limited to <strong>recombinant human insulin<\/strong> (commoditized, VBP pricing pressure) without ORMD-0801 differentiation<\/td><\/tr><tr><td><strong>CR Pharma Portfolio Optimization<\/strong><\/td><td>Divestment aligns with <strong>state-owned enterprise restructuring<\/strong>; proceeds likely redirected to <strong>innovative biologics or high-growth therapeutic areas<\/strong><\/td><\/tr><tr><td><strong>Valuation Benchmark<\/strong><\/td><td><strong>USD\u202f205 million for 17.87%<\/strong> implies <strong>~USD\u202f1.15 billion enterprise value<\/strong>; represents <strong>downround<\/strong> from 2020 peak expectations post-ORMD-0801 failure<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-transaction-outlook\">Transaction Outlook<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Phase<\/th><th>Activity<\/th><th>Timeline<\/th><\/tr><\/thead><tbody><tr><td><strong>Current<\/strong><\/td><td>Listing announcement; buyer solicitation<\/td><td>Q1\u202f2026<\/td><\/tr><tr><td><strong>Execution<\/strong><\/td><td>Auction\/bidding process; stake transfer completion<\/td><td>Q2\u202f2026<\/td><\/tr><tr><td><strong>Post-Divestment<\/strong><\/td><td>CR Pharma retains ~5.88% passive holding or full exit<\/td><td>2026-2027<\/td><\/tr><tr><td><strong>Proceeds Use<\/strong><\/td><td>Reinvestment into CR Pharma core pharmaceutical or healthcare services businesses<\/td><td>Ongoing<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Forward\u2011Looking Statements<\/strong><br>This brief contains forward\u2011looking statements regarding China Resources Pharmaceutical&#8217;s stake sale completion, Tianmai Bio valuation in post-ORMD-0801 environment, and CR Pharma capital reallocation strategy. Actual results may differ due to buyer interest levels in insulin manufacturing assets, pricing negotiations, and regulatory developments affecting Tianmai Bio&#8217;s remaining product portfolio.<a href=\"https:\/\/flcube.com\/\">-Fineline Info &amp; Tech<\/a><\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/flcube.com\/wp-content\/uploads\/2026\/02\/2026020900985_c.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of 2026020900985_c.\"><\/object><a id=\"wp-block-file--media-34ec8198-c3b6-462b-894e-6e2d5f760fdf\" href=\"https:\/\/flcube.com\/wp-content\/uploads\/2026\/02\/2026020900985_c.pdf\">2026020900985_c<\/a><a href=\"https:\/\/flcube.com\/wp-content\/uploads\/2026\/02\/2026020900985_c.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-34ec8198-c3b6-462b-894e-6e2d5f760fdf\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>China Resources Pharmaceutical Group Co., Ltd. (HKG:\u202f3320) announced plans to sell a 17.87% stake in&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,10],"tags":[2907,1976,3590],"class_list":["post-56838","post","type-post","status-publish","format-standard","hentry","category-company","category-deals","tag-china-resources-biopharmaceutical","tag-hkg-3320","tag-tianmai-biotechnology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>China Resources Pharma to Divest 17.87% Stake in Tianmai Bio for $205 Million - Insight, China&#039;s Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"China Resources Pharmaceutical Group Co., Ltd. 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(HKG:\u202f3320) announced plans to sell a 17.87% stake in Hefei Tianmai Biotechnology Co., Ltd., with a minimum listing price of RMB\u202f1.42 billion (USD\u202f205 million). The divestment follows ORMD-0801's failed NMPA approval in December\u202f2025, prompting CR Pharma to further reduce exposure to the insulin-focused biopharmaceutical company after multiple stake adjustments since 2016.","breadcrumb":{"@id":"https:\/\/flcube.com\/?p=56838#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/flcube.com\/?p=56838"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/flcube.com\/?p=56838#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/flcube.com\/"},{"@type":"ListItem","position":2,"name":"China Resources Pharma to Divest 17.87% Stake in Tianmai Bio for $205 Million"}]},{"@type":"WebSite","@id":"https:\/\/flcube.com\/#website","url":"https:\/\/flcube.com\/","name":"Insight, China's Pharmaceutical Industry","description":"Fineline Insights, Pharma Clarity","publisher":{"@id":"https:\/\/flcube.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/flcube.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/flcube.com\/#organization","name":"Fineline Infomation and Technology","alternateName":"Fineline Info & Tech","url":"https:\/\/flcube.com\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/flcube.com\/#\/schema\/logo\/image\/","url":"https:\/\/flcube.com\/wp-content\/uploads\/2024\/11\/Fineline-info-tech-scaled.jpg","contentUrl":"https:\/\/flcube.com\/wp-content\/uploads\/2024\/11\/Fineline-info-tech-scaled.jpg","width":2560,"height":1894,"caption":"Fineline Infomation and Technology"},"image":{"@id":"https:\/\/flcube.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/profile.php?id=61566606313834"]},{"@type":"Person","@id":"https:\/\/flcube.com\/#\/schema\/person\/19ad11870d326204db8524d3c3c5e66a","name":"Fineline Cube","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/89f733aaed3d2d91d7d6f45d0e9ab509e3004e8243c6e57620b36380684657f2?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/89f733aaed3d2d91d7d6f45d0e9ab509e3004e8243c6e57620b36380684657f2?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/89f733aaed3d2d91d7d6f45d0e9ab509e3004e8243c6e57620b36380684657f2?s=96&d=mm&r=g","caption":"Fineline Cube"},"sameAs":["https:\/\/flcube.com"],"url":"https:\/\/flcube.com\/?author=1"}]}},"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/flcube.com\/index.php?rest_route=\/wp\/v2\/posts\/56838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/flcube.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/flcube.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/flcube.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/flcube.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=56838"}],"version-history":[{"count":1,"href":"https:\/\/flcube.com\/index.php?rest_route=\/wp\/v2\/posts\/56838\/revisions"}],"predecessor-version":[{"id":56840,"href":"https:\/\/flcube.com\/index.php?rest_route=\/wp\/v2\/posts\/56838\/revisions\/56840"}],"wp:attachment":[{"href":"https:\/\/flcube.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=56838"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/flcube.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=56838"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/flcube.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=56838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}