{"id":7636,"date":"2024-03-19T10:48:01","date_gmt":"2024-03-19T02:48:01","guid":{"rendered":"https:\/\/flcube.com\/?p=7636"},"modified":"2024-10-18T10:53:21","modified_gmt":"2024-10-18T02:53:21","slug":"jiangsu-yahong-meditech-to-present-phase-iii-results-for-cervical-cancer-treatment-at-sgo-annual-meeting","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=7636","title":{"rendered":"Jiangsu Yahong Meditech to Present Phase III Results for Cervical Cancer Treatment at SGO Annual Meeting"},"content":{"rendered":"\n

Jiangsu Yahong Meditech Co., Ltd (Asieris, SHA: 688176<\/a>), a specialist in urogenital cancer treatments, is preparing to unveil key findings from a global multicenter Phase III clinical study on its Cevira (APL-1702) at the Society of Gynecologic Oncology (SGO) annual meeting. The study focuses on the treatment of high-grade squamous intraepithelial lesions (HSIL) of the cervix with APL-1702, a groundbreaking cold light photodynamic drug-device combination product used as a non-surgical therapy.<\/p>\n\n\n\n

The prospective, randomized, double-blind, placebo-controlled study aimed to assess the efficacy and safety of APL-1702 in treating HSIL, with the primary endpoint being the response rate at six months post-initial treatment. A response is defined as the normalization of cervical epithelial tissue pathology or a downgrade to low-grade squamous intraepithelial lesions (LSIL) of the cervix with clearance of HPV.<\/p>\n\n\n\n

Between November 2020 and July 2022, 402 eligible subjects were enrolled in the study. Preliminary results indicate that the response rate in the APL-1702 group was significantly higher than that in the placebo group, at 89.4% versus 41.1% (P=0.0001). Moreover, the HPV clearance rate in the APL-1702 group showed a notable improvement over the control group in the modified intention-to-treat (mITT) population, with rates of 28.0% and 19.8%, respectively. The study also reported a low incidence of TRAE (treatment-related adverse events) and SAE (serious adverse events) in both groups, highlighting the treatment’s safety profile.- Flcube.com<\/a><\/p>\n\n\n\n

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Jiangsu Yahong Meditech Co., Ltd (Asieris, SHA: 688176), a specialist in urogenital cancer treatments, is…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[316,17,1127,799],"class_list":["post-7636","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-asieris-pharmaceuticals","tag-clinical-trial-results","tag-sha-688176","tag-yahong-meditech"],"yoast_head":"\nJiangsu Yahong Meditech to Present Phase III Results for Cervical Cancer Treatment at SGO Annual Meeting - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Jiangsu Yahong Meditech Co., Ltd (Asieris, SHA: 688176), a specialist in urogenital cancer treatments, is preparing to unveil key findings from a global multicenter Phase III clinical study on its Cevira (APL-1702) at the Society of Gynecologic Oncology (SGO) annual meeting. 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