{"id":9332,"date":"2024-01-29T21:44:00","date_gmt":"2024-01-29T13:44:00","guid":{"rendered":"https:\/\/flcube.com\/?p=9332"},"modified":"2024-11-13T23:08:55","modified_gmt":"2024-11-13T15:08:55","slug":"bristol-myers-squibbs-subcutaneous-opdivo-shows-noninferiority-in-phase-iii-ccrcc-trial","status":"publish","type":"post","link":"https:\/\/flcube.com\/?p=9332","title":{"rendered":"Bristol Myers Squibb’s Subcutaneous Opdivo Shows Noninferiority in Phase III ccRCC Trial"},"content":{"rendered":"\n

Bristol Myers Squibb (BMS; NYSE: BMY<\/a>) this week announced preliminary Phase III data demonstrating that its subcutaneous formulation of Opdivo (nivolumab), developed in partnership with Halozyme Therapeutics (NASDAQ: HALO<\/a>), is noninferior to the intravenous version for patients with advanced or metastatic clear cell renal cell carcinoma (ccRCC).<\/p>\n\n\n\n

The equivalence trial successfully met its primary endpoints, including average serum concentration over 28 days and trough serum concentration at steady state, as well as the key secondary endpoint of noninferior objective response rate (ORR). The subcutaneous formulation achieved a median progression-free survival (PFS) of 7.23 months, compared to 5.65 months for the intravenous infusion, with both formulations exhibiting comparable safety profiles.- Flcube.com<\/a><\/p>\n\n\n\n

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Bristol Myers Squibb (BMS; NYSE: BMY) this week announced preliminary Phase III data demonstrating that…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAownpewDA:productID":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7,11],"tags":[429,428,16,17,1425,1578,849],"class_list":["post-9332","post","type-post","status-publish","format-standard","hentry","category-company","category-drug","tag-bms","tag-bristol-myers-squibb","tag-cancer","tag-clinical-trial-results","tag-halozyme-therapeutics","tag-nasdaq-halo","tag-nyse-bmy"],"yoast_head":"\nBristol Myers Squibb's Subcutaneous Opdivo Shows Noninferiority in Phase III ccRCC Trial - Insight, China's Pharmaceutical Industry<\/title>\n<meta name=\"description\" content=\"Bristol Myers Squibb (BMS; NYSE: BMY) this week announced preliminary Phase III data demonstrating that its subcutaneous formulation of Opdivo (nivolumab), developed in partnership with Halozyme Therapeutics (NASDAQ: HALO), is noninferior to the intravenous version for patients with advanced or metastatic clear cell renal cell carcinoma (ccRCC).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/flcube.com\/?p=9332\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bristol Myers Squibb's Subcutaneous Opdivo Shows Noninferiority in Phase III ccRCC Trial\" \/>\n<meta property=\"og:description\" content=\"Navigate the complexities of China\u2019s pharmaceutical industry with precision and clarity. 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