Novartis’ Atrasentan Shows Significant Reduction in Proteinuria in IgA Nephropathy Trial

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Novartis AG (NYSE: NVS), a Swiss pharmaceutical company, last week presented interim results for the primary endpoint of a Phase III trial for atrasentan in patients with IgA nephropathy (IgAN). The trial indicated that the endothelin A (ETA) receptor antagonist demonstrated a 36.1% reduction in proteinuria at 36 weeks compared to placebo. Additionally, the candidate exhibited a favorable safety profile with no new safety signals detected.

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Novartis is now preparing to submit the data for regulatory review in the following month, while it progresses the development of the investigational drug for other rare kidney diseases.- Flcube.com

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