Shanghai-based biotech company VelaVigo, specializing in bispecific/multi-specific antibodies and antibody drug conjugates (ADCs), has announced a global strategic partnership with US oncology firm Avenzo Therapeutics, Inc. This collaboration will facilitate the global development, manufacturing, and commercialization of VelaVigo’s Nectin4/TROP2 bispecific ADC, excluding Greater China, where VelaVigo retains the rights.
Details of the Partnership
The agreement grants Avenzo the rights to develop, manufacture, and commercialize the Nectin4/TROP2 bispecific ADC worldwide, except in Greater China. VelaVigo and Avenzo will jointly advance the global development and clinical application of the program. This strategic move is set to bolster the presence of both companies in the global oncology market.
Financial Terms and Milestones
As part of the deal, VelaVigo will receive an upfront payment and near-term milestone payment totaling up to USD 50 million. Additionally, the company is eligible to receive up to USD 750 million in subsequent milestone payments, along with tiered royalties based on sales. This financial arrangement underscores the significant potential of the Nectin4/TROP2 bispecific ADC in the global market.
Upcoming Milestones
The product is anticipated to undergo an Investigational New Drug (IND) filing in both the US and China in the coming year, marking a crucial step towards clinical trials and eventual market approval.
About VelaVigo
Established in 2021 with USD 50 million in angel funding, VelaVigo operations from hubs in Shanghai, China, and Boston, the United States. The company has quickly established itself as a leader in the development of innovative biotech solutions, particularly in the field of non-specific antibodies and ADCs.-Fineline Info & Tech
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