China-based AIM Vaccine Co., Ltd (HKG: 6660) has filed its mRNA-based shingles vaccine with the U.S. Food and Drug Administration (FDA), marking a milestone for the company’s entry into the global vaccine market. The submission follows promising preclinical data and positions AIM as a pioneer in mRNA shingles vaccine development, a category with no approved products worldwide.
Clinical Filing and Preclinical Results
AIM’s mRNA shingles vaccine demonstrated superior efficacy in preclinical animal trials compared to the existing recombinant subunit vaccine. The trials showed significantly higher specific T cell immunity, IgG antibody titers, and membrane antigen fluorescent antibody (FAMA) titers. These results highlight the vaccine’s potential to address a critical gap in herpes zoster prevention.
Market Opportunity
The global shingles vaccine market remains underserved, with a vaccination rate of just 0.1% among the target population. AIM’s mRNA vaccine could tap into this vast, unmet need, leveraging its innovative platform to deliver a more effective solution than current offerings.
DeepSeek Collaboration for Vaccine Innovation
In parallel, AIM has integrated DeepSeek’s large language models (LLMs) to accelerate vaccine discovery, design, and manufacturing. The partnership aims to optimize mRNA vaccine sequence design and stability using generative AI and deep learning. This strategic move underscores AIM’s commitment to leveraging cutting-edge technology to drive next-generation vaccine development.-Fineline Info & Tech
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