China-based CSPC Pharmaceutical Group Ltd (HKG: 1093) has announced clinical approval from the National Medical Products Administration (NMPA) for JMT108, an anti-PD-1/IL-15 bi-functional fusion protein. The targeted indication for this novel therapy is advanced malignant tumors, marking a significant step forward in the development of innovative cancer treatments in China.
Preclinical Data Highlights
Preclinical studies have demonstrated that JMT108 exhibits significant anti-tumor effects and good safety profiles across various malignant tumor models. These results suggest a high clinical development value, positioning JMT108 as a promising candidate in the expanding field of immunotherapies for advanced cancers.
Mechanism and Development Potential
JMT108 combines anti-PD-1 and IL-15 functionalities in a single bi-functional fusion protein. This innovative design aims to enhance the body’s immune response to tumors while minimizing potential side effects. The approval of JMT108 for clinical trials opens the door to further research into its efficacy and safety in human subjects, with the ultimate goal of improving treatment outcomes for patients with advanced malignant tumors.-Fineline Info & Tech
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