-
Zai Lab Partners with MediLink Therapeutics to Develop YL212 DLL3 ADC
•
Zai Lab Limited (NASDAQ: ZLAB, HKG: 9688), a China-based biopharmaceutical company, has announced a strategic partnership and exclusive worldwide license agreement with MediLink Therapeutics, a specialist in antibody drug conjugates (ADCs) founded in 2020. The agreement pertains to MediLink’s YL212, a novel DLL3 ADC program, highlighting Zai Lab’s commitment to…
-
LaNova Medicines and LegoChem Biosciences Partner to Develop Innovative ADC Product
•
Shanghai-based cancer therapy developer LaNova Medicines Ltd has entered into a research partnership agreement with South Korea-headquartered LegoChem Biosciences, Inc. Under this agreement, the two companies will leverage LaNova’s antibody assets and LCB’s antibody-drug conjugate (ADC) technology platform to develop an innovative ADC product. LaNova Medicines: A Clinical-Stage R&D CompanyEstablished…
-
Tot Biopharmaceutical and Shanghai Escugen Partner on ADC Development and Commercialization
•
China-based Tot Biopharmaceutical International Co., Ltd (HKG: 1875) has announced a strategic partnership with Shanghai Escugen, aimed at advancing the research, development, and manufacturing of antibody-drug conjugates (ADCs). The collaboration extends from late clinical development through to the commercialization phase, with financial details undisclosed. Leveraging Tot Bio’s Expertise in ADC…
-
Tot Biopharmaceutical Partners with Suzhou Smart Nuclide on Radioactive Drug Development
•
China-based Tot Biopharmaceutical International Co., Ltd (HKG: 1875) has announced a strategic partnership with Suzhou Smart Nuclide Pharmaceutical Technology Company, a move focused on the development of radioactive drugs based on conjugate technology. Complementary Expertise in RadiopharmaceuticalsUnder the terms of the partnership, Tot Bio will offer a comprehensive antibody conjugate…
-
Sichuan Biokin Pharmaceutical Gets NMPA Approval for Two Clinical Studies on Cancer Therapies
•
Sichuan Biokin Pharmaceutical Co., Ltd (SHA: 688506), a China-based pharmaceutical company, has announced receiving approval from the National Medical Products Administration (NMPA) to conduct two clinical studies. One study will investigate the combination of its drug candidate BL-B01D1 with osimertinib (Tagrisso) for the treatment of locally advanced or metastatic non-small…
-
Evopoint Biosciences Gets CDE Approval for Phase I/II Study of XNW27011 ADC
•
Suzhou Evopoint Biosciences Co., Ltd., a China-based pharmaceutical company, has announced receiving approval from the Center for Drug Evaluation (CDE) to conduct a Phase I/II clinical study for its antibody-drug conjugate (ADC), XNW27011. The study will focus on locally advanced unresectable or metastatic malignant solid tumors expressing Claudin 18.2 (CLDN18.2).…
-
CSPC Pharmaceutical Group Gets NMPA Approval for SYS6010 ADC Clinical Trial
•
China-based CSPC Pharmaceutical Group Ltd (HKG: 1093) has announced that it has received clinical trial approval from the National Medical Products Administration (NMPA) for its antibody-drug conjugate (ADC), SYS6010, which is intended for the treatment of advanced solid tumors. Pre-Clinical Studies and Patent Protection for SYS6010Pre-clinical studies have demonstrated that…
-
RemeGen Ltd Partners with Shandong Cancer Hospital for ADC Development and Integrated System
•
RemeGen Ltd (HKG: 9995) has announced a strategic partnership with Shandong Cancer Hospital to establish a clinics-centered integrated system that spans the pharmaceutical industry, academia, and research fields, with a focus on antibody-drug conjugate (ADC) development. RemeGen’s ADC Achievements and PipelineRemeGen’s disitamab vedotin marked a significant milestone as the first…
-
RemeGen’s Disitamab Vedotin (RC48) Clears for Phase I Study in HER2-Positive Tumors
•
RemeGen Ltd (HKG: 9995), a biopharmaceutical company, has announced that it has received approval from the National Medical Products Administration (NMPA) to conduct a Phase I clinical study for its antibody-drug conjugate (ADC) candidate, disitamab vedotin (RC48). This single-arm, open, single-center study aims to evaluate the safety and maximum tolerable…
-
Huadong Medicine Reports 9.12% YOY Revenue Growth and 13.24% Increase in Net Profits for 2022
•
Huadong Medicine Co., Ltd (SHE: 000963), a leading China-based pharmaceutical company, has released its 2022 financial report, demonstrating robust growth with revenues of RMB 37.715 billion (USD 5.5 billion), an increase of 9.12% year-on-year (YOY), and net profits of RMB 2.598 billion (USD 379.3 million), marking a 13.24% YOY increase.…
-
Overland ADCT BioPharma Achieves Primary Endpoint in Zynlonta Phase II Study for R/R DLBCL
•
Joint venture Overland ADCT BioPharma (CY) Ltd, a partnership between China’s Overland Pharmaceuticals and Swiss firm ADC Therapeutics SA (NYSE: ADCT), announced that the primary endpoint has been reached in a Phase II regulatory study. The study assessed the efficacy and safety of Zynlonta (loncastuximab tesirine), an antibody-drug conjugate (ADC)…
-
Porton Pharma Solutions Expands with Biomacromolecules R&D and Manufacturing Center in Shanghai
•
China-based Contract Development and Manufacturing Organization (CDMO) Porton Pharma Solutions has initiated the construction of a state-of-the-art biomacromolecules research and development (R&D) and manufacturing center in the Wai Gao Qiao Tax-Free Zone of Shanghai. This new facility aims to offer biopharmaceutical companies and new drug developers comprehensive one-stop CDMO services,…
-
Hangzhou Baikai Biomedical and Leads Biolabs Partner to Develop Innovative ADCs
•
China-based Hangzhou Baikai Biomedical Co., Ltd and Leads Biolabs Inc. have announced a partnership aimed at developing multiple novel antibody-drug conjugates (ADCs). The collaboration combines the expertise of both companies to advance the development of innovative cancer treatments. Financial details of the partnership have not been disclosed. Baikai Bi’s ADC…
-
Mabwell’s 9MW2821 ADC Shows Positive Signals in Solid Tumor Clinical Data
•
China-based Mabwell (Shanghai) Bioscience Co., Ltd (SHA: 688062) has announced preliminary clinical data for its antibody-drug conjugate (ADC) 9MW2821, which targets Nectin-4. The data demonstrated positive therapeutic signals in multiple solid tumors and exhibited a good safety profile at the recommended Phase II dosage (RP2D). Mechanism of Action and Pharmaceutical…
-
BioNTech and Duality Biologics Ink Exclusive License Agreement for ADC Assets
•
Germany-based BioNTech SE (NASDAQ: BNTX) and China-headquartered Duality Biologics (Suzhou) Co., Ltd have announced that they have entered into exclusive license and collaboration agreements focused on two of Duality’s antibody-drug conjugate (ADC) assets. BioNTech is set to acquire all development, manufacturing, and commercialization rights to these two assets globally, excluding…
-
CSPC Pharmaceutical Receives FDA Approval for Phase I Study of CPO301 in Lung Cancer
•
China-based CSPC Pharmaceutical Group Ltd (HKG: 1093) has announced that it has received approval from the US Food and Drug Administration (FDA) to conduct a Phase I clinical study assessing the safety, pharmacokinetics, and preliminary efficacy of its antibody-drug conjugate (ADC) CPO301 in patients with advanced lung cancer characterized by…
-
Shanghai Fosun Pharma Commences Phase III Trial for HER2-Targeted FS-1502
•
Shanghai Fosun Pharmaceutical (Group) Co., Ltd (SHA: 600196, HKG: 2196), a prominent Chinese pharmaceutical company, has announced the start of a Phase III clinical study in the Chinese mainland for its HER2-targeted antibody drug conjugate (ADC), FS-1502. The study is focused on the treatment of HER2-positive unresectable, locally advanced, or…
-
Akeso Biopharma and LaNova Medicines Collaborate on Clinical Studies for Cancer Therapies
•
China-based Akeso Biopharma (HKG: 9926) has announced a strategic partnership with fellow Chinese firm LaNova Medicines to advance a series of clinical studies. The collaboration will assess a combination regimen of Akeso’s AK112, a bispecific antibody (BsAb) targeting programmed death-1 (PD-1) and vascular endothelial growth factor (VEGF), with LaNova’s LM-302,…
-
Akeso Biopharma and LaNova Medicines Collaborate on AK112 and LM-302 Combo for Solid Tumors
•
China-based Akeso Biopharma (HKG: 9926) has entered into a strategic partnership with compatriot firm LaNova Medicines to advance a series of clinical studies. These studies will assess the combination regimen of Akeso’s AK112, a bispecific antibody (BsAb) targeting programmed death-1 (PD-1) and vascular endothelial growth factor (VEGF), alongside LaNova’s LM-302,…
-
Sihuan Pharmaceutical’s KM501 Receives Clinical Trial Approval for HER2-Positive Tumors
•
China-based Sihuan Pharmaceutical Holdings Group Ltd (HKG: 0460) has announced that it has received clinical trial approval from the National Medical Products Administration (NMPA) for its XZP-KM501 (KM501) in solid tumors with HER2 positive, middle to low-expression. This marks a significant step forward in the development of innovative treatments for…
