By Fineline Cube 
PackGene LLC, a global leader in gene‑therapy contract development and manufacturing, and the Children’s Medical Research Institute (CMRI) of Australia have signed a licensing agreement to jointly commercialize a next‑generation, high‑throughput adeno‑associated virus (AAV) capsid screening kit.
What the Kit Offers
- DNA‑barcoded AAV library that enables rapid in‑vitro, ex‑vivo, and in‑vivo screening of thousands of capsids in a single experiment.
- One‑stop solution: from library design to data analysis, the kit streamlines the entire vector‑selection workflow.
- Optimized capsids – customers will gain access to proprietary AAV variants from PackGene and CMRI, engineered for superior tissue specificity, reduced immunogenicity, and higher production yields.
Partnership Roles
| Role | Partner | Responsibility |
|---|---|---|
| Production & Commercialization | PackGene | Large‑scale manufacturing, global distribution, customer support |
| Capsid Development & Licensing | CMRI & PackGene | Development of novel, tissue‑specific AAV capsids; licensing of proprietary variants |
| Technology Transfer | Both | Joint training, data sharing, and continuous improvement of the screening platform |
Impact on Gene‑Therapy R&D
- Accelerated discovery – Researchers can now identify optimal capsids within weeks rather than months, cutting down development timelines.
- Cost efficiency – The kit’s barcoded design reduces reagent usage and eliminates the need for multiple parallel experiments.
- Global reach – PackGene’s established CDMO footprint ensures that the kit is available to academic, biotech, and pharmaceutical partners worldwide.
Looking Ahead
The collaboration underscores PackGene’s commitment to expanding its AAV technology portfolio and positions the company as a preferred partner for vector discovery. CMRI will continue to contribute its expertise in preclinical delivery and safety profiling, ensuring that the newly licensed capsids meet the stringent demands of next‑generation gene‑therapy therapies.-Fineline Info & Tech