-
Overland ADCT BioPharma Launches Global Phase III Trial for Zynlonta in DLBCL
•
Overland ADCT BioPharma, a joint venture between China’s Overland Pharmaceuticals and Switzerland’s ADC Therapeutics SA (NYSE: ADCT), announced the initiation and first patient dosing of the global Phase III LOTIS-5 trial for Zynlonta (loncastuximab tesirine), an anti-CD19 antibody-drug conjugate (ADC). The study will evaluate Zynlonta in combination with rituximab as…
-
Bio-Thera Solutions Doses First Patient in BAT8006 Phase I Study for Solid Tumors
•
Guangzhou-based Bio-Thera Solutions (SHA: 688177) announced that the first patient has been dosed in a Phase I clinical study of BAT8006, an in-house developed antibody drug conjugate (ADC) targeting folate receptor alpha (FRα), for advanced solid tumors. The multi-center, open-label trial will assess the drug’s safety, tolerability, and preliminary efficacy.…
-
Bangbang Robot Raises USD 14.9M in Series B to Expand Mobility Tech
•
Shanghai-based Bangbang Robot Co., Ltd, a developer of assisted mobility technology, has raised nearly RMB 100 million ($14.9 million) in a Series B financing round co-led by Lake Bleu Capital and BioTrack Capital, with participation from 01VC and Long Hill Capital. The funds will support manufacturing, installation of its products,…
-
OBI Pharma Halts OBI 888 Trial Over Manufacturing Costs, Shifts Focus to Globo H ADC
•
Taiwan-based OBI Pharma (TPEx: 4174) announced the discontinuation of a Phase I/II trial for its Globo H antibody OBI 888, citing manufacturing cost challenges. The decision comes despite preliminary data showing the antibody was safe, well-tolerated, and demonstrated efficacy. Reasons for HaltThe trial was stopped because OBI 888 required a…
-
Hengrui Medicine’s SHR8554 Accepted for NMPA Review in Postoperative Pain
•
China-based Jiangsu Hengrui Medicine Co., Ltd (SHA: 600276) announced that its market filing for SHR8554, an injectable drug candidate for moderate to severe postoperative pain, has been accepted by the National Medical Products Administration (NMPA). The drug, a small-molecule μ-opioid receptor (MOR) agonist, met superiority standards in a Phase III…
-
Insilico Medicine Identifies Novel ALS Therapeutic Targets via AI Platform PandaOmics
•
China-based Insilico Medicine announced the identification of multiple novel therapeutic targets for amyotrophic lateral sclerosis (ALS) using its AI-driven platform PandaOmics, in collaboration with Answer ALS. The findings, published in Frontiers in Aging Neuroscience on June 28, highlight 17 high-confidence and 11 new targets validated in ALS models. Research Highlights…
-
CSPC Pharmaceutical’s JMT103 Anti-RANKL Antibody Prioritized for CDE Review
•
China-based CSPC Pharmaceutical Group Ltd (HKG: 1093) announced that its market filing for JMT103, an anti-RANKL monoclonal antibody (mAb) developed by subsidiary Shanghai JMT Biotechnology Co., Ltd, has been prioritized for review by the Center for Drug Evaluation (CDE). The drug is designed to address deficiencies in existing RANKL antibodies,…
-
Gan & Lee Pharmaceuticals’ GZR4 Ultra-Long-Acting Insulin Receives Clinical Trial Approval
•
China-based Gan & Lee Pharmaceuticals (SHA: 603087) announced that its Category 1 therapeutic biologic product GZR4 has received clinical trial approval for treating diabetes. GZR4 is an ultra-long-acting insulin designed for once-weekly subcutaneous injection, addressing the need for more stable and convenient diabetes management. Product ProfileCurrent long-acting basal insulin analogs…
