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Sirnaomics Initiates Phase I Clinical Trial for Anticoagulant Drug Candidate STP122G
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Sirnaomics Ltd (HKG: 2257) has announced the first systemic dosing of a Phase I clinical trial for its leading RNAi drug candidate, STP122G, an anticoagulation treatment. STP122G, developed using Sirnaomics’ GalNAc RNAi delivery platform technology GalAhead, targets Factor XI and has broad applicability across various disease indications, including the potential…
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CANbridge Pharmaceuticals’ Maralixibat Approved by NMPA for Alagille Syndrome
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China-based rare disease specialist CANbridge Pharmaceuticals Inc., (HKG: 1228) has announced receiving market approval from the National Medical Products Administration (NMPA) for its drug maralixibat (CAN108). The drug is approved to treat pruritus due to cholestasis in patients with Alagille Syndrome (ALGS) aged 1 year and above. Understanding Alagille Syndrome…
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Innovent Biologics Partners with Merck KGaA to Test KRAS Inhibitor Combo in NSCLC
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China-based Innovent Biologics (HKG: 1801) has announced a clinical study and supply agreement with German pharmaceutical giant Merck KGaA (NYSE: MRK). The collaboration aims to explore the combination of Innovent’s KRAS G12C inhibitor, IBI351, and Merck’s Erbitux (cetuximab) in patients with advanced non-small cell lung cancer (NSCLC) harboring the KRAS…
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Shenzhen Abrobo Medical Robot Secures RMB 100 Million in Series A Financing for Robotic Development
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Shenzhen Abrobo Medical Robot Co, Ltd has reportedly raised RMB 100 million via a Series A financing round, marking a significant step forward for the company. The round was led by Guozhong Capital, with additional investments from Lenovo Capital and Long Hill Capital. The funds will be directed towards accelerating…
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Akeso Biopharma’s Ebronucimab NDA Accepted for Review by China’s NMPA
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China-based Akeso Biopharma (HKG: 9926) has announced that the National Medical Products Administration (NMPA) has accepted two New Drug Application (NDA) filings for its proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor ebronucimab. The applications are for the treatment of primary hypercholesterolemia and mixed hyperlipidemia, as well as heterozygous familial hypercholesterolemia…
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Eikon Therapeutics Inks Licensing Deals and Raises Funds for Drug Pipeline Expansion
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US biotech company Eikon Therapeutics has announced three in-licensing deals this week, one of which includes a partnership with China-based Impact Therapeutics. The agreement grants Eikon exclusive rights to co-develop, manufacture, and commercialize PARP1 inhibitors, including IMP1734, in markets outside of Greater China. The financial details of the licensing fee…
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Sino Biopharmaceutical’s Subsidiary invoX Completes Additional Investment in pHion Therapeutics
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The UK-based invoX Pharma Ltd, a wholly-owned subsidiary of China’s Sino Biopharmaceutical Ltd (HKG: 1177), has revealed the completion of a second tranche of investment in the Belfast-based company pHion Therapeutics. Specific details regarding the first or second tranche of investment and invoX’s current stake-holding in pHion have not been…
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Ucello Therapeutics Secures RMB 150 Million in Series A+ Financing for CAR-T Cell Therapy
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Ucello Therapeutics, a developer of allogeneic universal chimeric antigen receptor (CAR)-T cell therapies based in Chengdu, has reportedly raised RMB 150 million (USD 21.2 million) in a Series A+ financing round. The funding was led by Juke Investment, with contributions from Guozhong Capital and Penglai Capital, as well as existing…
