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Porton Pharma and Dragon Sail Join Forces to Enhance ADC Drug Development
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China-based Contract Development and Manufacturing Organization (CDMO) Porton Pharma Solutions has entered into a strategic partnership with fellow Chinese firm Dragon Sail Pharmaceutical (Shanghai) Co., Ltd. This collaboration aims to focus on the research and development (R&D), manufacturing, and supply chain of antibody drug conjugates (ADCs), with no financial terms…
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GSK’s Jemperli Combo Shows Improved PFS in Phase III Ovarian Cancer Trial
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UK-based GSK plc (NYSE: GSK) has announced a positive readout from the Phase III FIRST-ENGOT-OV44 trial for Jemperli (dostarlimab), a programmed death-1 (PD-1) inhibitor, when combined with Zejula (niraparib) for the first-line treatment of advanced ovarian cancer. The trial evaluated the addition of Jemperli to the standard of care carboplatin-paclitaxel…
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Pfizer’s Braftovi Receives FDA Approval for Metastatic Colorectal Cancer Treatment
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US-based Pfizer (NYSE: PFE) has announced receiving an indication extension approval from the US Food and Drug Administration (U.S. FDA) for Braftovi (encorafenib) in combination with cetuximab and mFOLFOX6 (fluorouracil, leucovorin, and oxaliplatin) for the treatment of patients with metastatic colorectal cancer (mCRC) with a BRAF V600E mutation. Braftovi’s Existing…
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Eli Lilly’s Zepbound Receives FDA Approval for Moderate-to-Severe OSA and Obesity
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US pharmaceutical giant Eli Lilly & Co. (NYSE: LLY) has revealed that the US Food and Drug Administration (FDA) has granted another indication approval for its drug Zepbound (tirzepatide), marking it as the first and only prescription medicine for adults with moderate-to-severe obstructive sleep apnea (OSA) and obesity. Zepbound can…
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Novo Nordisk’s Alhemo Receives FDA Approval for Hemophilia A and B Prophylaxis
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Denmark-based Novo Nordisk A/S (NYSE: NVO) has announced that the US Food and Drug Administration (FDA) has granted marketing approval for its Alhemo (concizumab-mtci) injection. The drug is indicated as a once-daily prophylaxis to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients aged 12 years…
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Boehringer Ingelheim-SEC Joint Incubator Launches in Shenzhen’s Luohu District
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On December 23, the Boehringer Ingelheim-SEC Joint innovative incubator was inaugurated in Luohu District, Shenzhen. This marks the establishment of the first high-specification innovation platform in the Guangdong-Hong Kong-Macau Greater Bay Area (GBA), co-hosted by a multinational pharmaceutical company and an innovation center. State-of-the-Art Facilities and Support for Biopharmaceutical EntrepreneursThe…
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CStone Pharmaceuticals Initiates First-in-Human Trial for PD-1/VEGF/CTLA-4 Trispecific Antibody CS2009
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China-based CStone Pharmaceuticals (HKG: 2616) has announced the clinical filing for its CS2009, a PD-1/VEGF/CTLA-4 trispecific antibody, in Australia. This first-in-human study is registered and published on Clinicaltrials.gov with the NCT number: NCT06741644. Innovative Design and Mechanism of CS2009CS2009 boasts an innovative molecular design that simultaneously targets PD-1, VEGFA, and…
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Becton, Dickinson and Co. Launches RMB1.332 Billion Factory in Jiangsu for Pre-Filled Syringes
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US-based Becton, Dickinson and Co., (BD) has officially put into operation its new factory in Yixing, Jiangsu province, with an investment worth RMB1.332 billion (USD182.5 million). This plant marks BD’s third world-class local production base in China and is now the central facility for local manufacturing of BD pre-filled flush…
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C.Q. Pharmaceutical Holding to Come Under SASAC’s Indirect Control via Genertec Acquisition
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C.Q. Pharmaceutical Holding Co., Ltd (SHE: 000950), a Chongqing-based pharmaceutical company, is set to be indirectly controlled by China’s State-owned Assets Supervision and Administration Commission of the State Council (SASAC). The company has entered into an acquisition agreement with China General Technology (Group) Holding Co Ltd (Genertec), a centrally administered…
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Yifan Pharmaceutical’s Evive Biotech Receives ANVISA Approval for Ryzneuta
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China-based Yifan Pharmaceutical Co., Ltd (SHE: 002019) has announced that its subsidiary, Evive Biotech Ltd, has received marketing approval from the Brazil National Health Surveillance Agency (ANVISA) for Ryzneuta (efbemalenograstim alfa, F-627). This approval follows previous marketing nods in China, the United States, and the European Union. Ryzneuta (F-627): A…
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Changchun BCHT Biotechnology Receives NMPA Approval for HSV-2 mRNA Vaccine LVRNA101
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Changchun BCHT Biotechnology Co., Ltd (SHA: 688276), a China-based biotechnology company, has announced receiving clinical trial approval from the National Medical Products Administration (NMPA) for its mRNA vaccine, LVRNA101. The vaccine is designed to prevent genital herpes caused by herpes simplex virus type 2 (HSV-2) infection. HSV-2 and the Need…
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Shenzhen Chipscreen Biosciences Gets NMPA Approval for CS231295 Solid Tumor Study
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Shenzhen Chipscreen Biosciences Co., Ltd (SHA: 688321), a China-based biopharmaceutical company, has announced receiving the go-ahead from the National Medical Products Administration (NMPA) to conduct a clinical study for its drug candidate CS231295 in advanced solid tumors. CS231295: A Promising Multi-Target InhibitorCS231295 is a multi-target protein kinase inhibitor that has…
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Jiangsu Hengrui Pharmaceuticals Gets NMPA Approval to Test SHR-1681 in Clinical Trials
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Jiangsu Hengrui Pharmaceuticals Co., Ltd. (SHA: 600276) has announced that it has received approval from the National Medical Products Administration (NMPA) to proceed with clinical testing of its Category 1 biologic product, SHR-1681. Novel Biologic Product SHR-1681The product, SHR-1681, is designed to specifically bind to antigens present on the surface…
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CSPC Pharmaceutical’s SYH9017 Receives NMPA Clearance for Weight Management Clinical Trial
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China-based CSPC Pharmaceutical Group Co., Ltd. (HKG: 1093) has announced clinical clearance from the National Medical Products Administration (NMPA) for its SYH9017, a biosimilar version of Denmark-based Novo Nordisk’s (NYSE: NVO) weight loss drug semaglutide (Ozempic/Wegovy). The clearance allows SYH9017 to proceed to clinical trials focused on weight management for…
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CSPC Pharmaceutical Group Receives NMPA Approval for Two Antibody-Drug Conjugates
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China-based CSPC Pharmaceutical Group Co., Ltd. (HKG: 1093) has announced that it has received separate clinical trial approvals from the National Medical Products Administration (NMPA) for its antibody drug conjugates (ADCs), SYS6005 and SYS6043. Pre-Clinical Success and Potential ApplicationsBoth SYS6005 and SYS6043, classified as Category 1 biologic products with undisclosed…
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CanSino Biologics Initiates Phase I/II Study for CS-2036 Polio Vaccine with Gates Foundation Support
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CanSino Biologics (SHA: 688185, HKG: 6185) has announced the initiation of a Phase I/II study for its CS-2036, a recombinant polio vaccine, in Indonesia with financial support from the Bill & Melinda Gates Foundation. This development is accompanied by the first subject enrollment in the Phase I trial. Additionally, the…
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Innovent Biologics’ Taletrectinib Wins NMPA Approval for ROS1+ NSCLC Treatment
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China-based Innovent Biologics, Inc. (HKG: 1801) has announced receiving marketing approval from the National Medical Products Administration (NMPA) for its taletrectinib, a second-generation ROS1 tyrosine kinase inhibitor. The drug is now approved for use in treating adult patients with ROS1 positive locally advanced or metastatic non-small cell lung cancer (NSCLC)…
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MicroPort Scientific Corp. Receives NMPA Approval for FireRaptor Coronary Atherectomy System
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Shanghai-based medical device giant MicroPort Scientific Corp. (HKG: 0853) has announced receiving marketing approval from the National Medical Products Administration (NMPA) for its FireRaptor coronary rotational atherectomy system. The system includes a rotational atherectomy instrument, disposable coronary artery rotational atherectomy catheter, and rotational atherectomy guide wire. First-Homegrown Coronary Rotational Atherectomy…
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Biopharma Company TransThera Sciences (Nanjing) Gets Green Light for HK IPO
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On December 20, 2024, the China Securities Regulatory Commission confirmed the listing filing for TransThera Sciences (Nanjing), Inc., to proceed with its initial public offering (IPO) in Hong Kong. Proposed Share Issuance and ConversionTransThera Sciences plans to issue up to 146 million overseas-listed ordinary shares on the Hong Kong Stock…
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YolTech Therapeutics’ YOLT-201 Advances in ATTR Treatment Clinical Trial
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Shanghai, China, December 21, 2024 — YolTech Therapeutics today announced that its proprietary in vivo gene-editing drug, YOLT-201, has successfully completed the dose-escalation phase in Phase I clinical trials for the treatment of transthyretin amyloidosis (ATTR) and is set to enter the dose-expansion phase. YOLT-201: A Novel Gene-Editing Therapy for…
