Hanx Biopharma Prices HKEX IPO to Fund Bispecific Antibody Pipeline

Hanx Biopharma Prices HKEX IPO to Fund Bispecific Antibody Pipeline

Hanx Biopharmaceuticals (Wuhan) Co., Ltd. released its prospectus for a Hong Kong Stock Exchange listing (HKG: 3378), offering 18,321,000 H‑shares at HK$28‑32 per share to raise up to HK$586 million (≈ US$75 M). The company is developing a pipeline of bispecific antibodies led by HX009, an anti‑PD‑1/SIRPα fusion protein in Phase 2 trials for oncology.

IPO Details

ItemDetails
ExchangeHong Kong Stock Exchange (HKG: 3378)
Shares Offered18,321,000 H‑shares
Price RangeHK$28‑32 per share
Maximum RaiseHK$586 million (≈ US$75 M)
Use of ProceedsAdvance HX009 Phase 3 trials; expand manufacturing; fund preclinical pipeline
Listing DateExpected Q1 2026

Company & Pipeline Overview

FoundedFocusCore Technology
UnspecifiedStructural biology, translational medicine, clinical developmentBispecific antibody fusion proteins, multi‑target kinase inhibitors

Clinical-Stage Pipeline

AssetTarget/MechanismIndicationStage
HX009Anti‑PD‑1/SIRPα bispecific fusion proteinOncologyPhase 2
HX301Multi‑target kinase inhibitorOncologyPhase 1/2
HX044CTLA‑4/SIRPα bispecific fusion proteinOncologyPhase 1
Preclinical7 candidates (ADCs, bispecifics, mAbs)Autoimmune & oncologyDiscovery/IND‑enabling

Strategic Implications

  • For Hanx: IPO proceeds will accelerate HX009 into Phase 3, fund manufacturing scale‑up for bispecific platforms, and advance a deep preclinical pipeline addressing oncology and autoimmune diseases.
  • For Investors: Offers exposure to China’s bispecific antibody boom with a platform validated by multiple clinical assets; HX009’s PD‑1/SIRPα mechanism is differentiated from standard PD‑1 monotherapy.
  • For Market: Adds a new competitor in the crowded PD‑1 space but with novel bispecific approach; potential for global out‑licensing if Phase 2 data readout is positive in 2026.

Forward‑Looking Statements
This brief contains forward‑looking statements regarding the IPO timeline, HX009 clinical development, and market penetration. Actual results may differ due to market conditions, clinical risks, or competitive dynamics.-Fineline Info & Tech